biological source
bovine
Quality Level
sterility
aseptically filled
Assay
28-32% protein basis (biuret)
form
solution
purified by
heat shock fractionation
contains
0.1% sodium azide as preservative
10-15 mg/gram protein octanoic acid as stabilizer
origin
USA origin
concentration
28-32% (biuret)
30%±2% in 0.85% sodium chloride
technique(s)
cell culture | mammalian: suitable
UniProt accession no.
storage temp.
2-8°C
Gene Information
bovine ... ALB(280717)
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General description
Bovine serum albumin (BSA), a non-glycosylated globular protein, is synthesized in the liver without the use of prosthetic groups or other additives, making it one of the few plasma proteins without carbohydrate groups. BSA reveals distinct binding sites with varying specificities. Site-I and site-II are the most important ones, located in the hydrophobic cavities of subdomains IIA and IIIA, respectively.
Application
Bovine Serum Albumin solution has been used:
- in the incubation of 108 colony-forming units S. aureus for quantitative suspension assay to evaluate the antibacterial efficacy
- as a component in bacterial broth culture as organic matter loading for control experiments to study the microbicidal impact of the sesamoid bone against Staphylococcus aureus
- as organic matter loading in Ham′s F12 culture medium for quantitative suspension tests to observe the effect of antimicrobial action of the antiseptics
Biochem/physiol Actions
Bovine serum albumin (BSA) functions as a transport carrier for drugs. It is primarily used as a test model for studying albumin interactions with strong pharmaceutical agents. The ability of BSA to interact with many aromatic and hydrophobic molecules in the bloodstream makes it useful. In cell culture media, bovine serum albumin is frequently used as a protein supplement. The fluorescent property of BSA aids in emitting intensely upon excitation.
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
含少量动物源组分生物产品
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N Kapalschinski et al.
Burns : journal of the International Society for Burn Injuries, 39(6), 1221-1225 (2013-05-15)
Wound infection is one of the major complications in acute and chronic wound healing. Antiseptic solutions and wound irrigating agents are routinely used for therapy and prevention in healthcare today. Even if wound exudate contains total protein concentrations up to
Bovine serum albumin
2018 IEEE International Interconnect Technology Conference (IITC), 1045-1045 (2016)
The NMR tube bioreactor
Chatzikonstantinou AV, et al.
Test, 633, 71-101 (2020)
Gerald Müller et al.
Chemico-biological interactions, 145(3), 331-336 (2003-05-07)
Anatomically intact articular cartilage in form of sesamoid bones from metacarpophalangeal joints of 2-year-old cows was tested for its influence on the microbicidal effect of the iodophore Betaisodona, the bispyridinamine Octenisept, and the biguanide Lavasept. Comparisons were carried out in
The NMR tube bioreactor
Chatzikonstantinou AV, et al.
Methods in Enzymology, 633, 71-101 (2020)
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