A3168
N-(4-Aminobutyl)-2-naphthalenesulfonamide hydrochloride
analytical standard, for drug analysis
Synonym(s):
W-12
Sign In to View Organizational & Contract Pricing.
Select a Size
About This Item
Empirical Formula (Hill Notation):
C14H18N2O2S · HCl
CAS Number:
Molecular Weight:
314.83
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
InChI
1S/C14H18N2O2S.ClH/c15-9-3-4-10-16-19(17,18)14-8-7-12-5-1-2-6-13(12)11-14;/h1-2,5-8,11,16H,3-4,9-10,15H2;1H
SMILES string
Cl[H].NCCCCNS(=O)(=O)c1ccc2ccccc2c1
InChI key
WYFVKUWCEVMLOL-UHFFFAOYSA-N
form
powder
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
color
yellow
solubility
H2O: soluble
application(s)
forensics and toxicology
pharmaceutical (small molecule)
veterinary
format
neat
storage temp.
2-8°C
Quality Level
General description
Stock solutions of approx. 5 mM are suggested. Stocks should be stable for at least 6 months when stored at 4 °C
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Biochem/physiol Actions
A calmodulin antagonist; inhibits Ca2+/calmodulin activated phosphodiesterase and myosin light chain kinase.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Masahiko Yamagishi et al.
Cytoskeleton (Hoboken, N.J.), 77(9), 351-361 (2020-08-28)
In in vitro microtubule gliding assays, most kinesins drive the rotation of gliding microtubules around their longitudinal axes in a corkscrew motion. The corkscrewing pitch is smaller than the supertwisted protofilament pitch of microtubules, indicating that the corkscrewing pitch is
Azusa Kage et al.
The Journal of experimental biology, 223(Pt 5) (2020-01-29)
The way the unicellular, biflagellated, green alga Chlamydomonas orients upward has long been discussed in terms of both mechanics and physiology. In this study, we focus on the mechanics, i.e. the 'passive' mechanisms, of gravitaxis. To rotate the body upwards
Ryuichi Tatsumi et al.
American journal of physiology. Cell physiology, 296(4), C922-C929 (2009-01-23)
When skeletal muscle is stretched or injured, myogenic satellite cells are activated to enter the cell cycle. This process depends on nitric oxide (NO) production by NO synthase (NOS), matrix metalloproteinase activation, release of hepatocyte growth factor (HGF) from the
Rosa Gabriela Beltrán-López et al.
BMC evolutionary biology, 18(1), 56-56 (2018-04-22)
Volcanic and tectonic activities in conjunction with Quaternary climate are the main events that shaped the geographical distribution of genetic variation of many lineages. Poeciliopsis infans is the only poeciliid species that was able to colonize the temperate highlands of
H Hidaka et al.
Proceedings of the National Academy of Sciences of the United States of America, 78(7), 4354-4357 (1981-07-01)
N-(6-Aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7) and its derivatives are putative calmodulin antagonists that bind to calmodulin and inhibit Ca2+/calmodulin-regulated enzyme activities. Autoradiographic studies using tritiated W-7 showed that this compound penetrates the cell membrane, is distributed mainly in the cytoplasm, and inhibits proliferation
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service