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Merck
CN

B1143000

Bromazepam

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

7-Bromo-5-(2-pyridyl)-3H-1,4-benzodiaxepin-2(1H)-one

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About This Item

Empirical Formula (Hill Notation):
C14H10BrN3O
CAS Number:
1812-30-2
Molecular Weight:
316.15
NACRES:
NA.24
PubChem Substance ID:
329773169
UNSPSC Code:
41116107
MDL number:
MFCD00057902

Key Documents

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InChI key

VMIYHDSEFNYJSL-UHFFFAOYSA-N

SMILES string

O=C(CN=C1C2=CC=CC=N2)NC3=C1C=C(Br)C=C3

InChI

1S/C14H10BrN3O/c15-9-4-5-11-10(7-9)14(17-8-13(19)18-11)12-3-1-2-6-16-12/h1-7H,8H2,(H,18,19)

grade

pharmaceutical primary standard

API family

bromazepam

manufacturer/tradename

EDQM

Gene Information

human ... GABRA2(2555)

drug control

kontrollierte Droge in Deutschland, regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal); Pszichotróp anyag / Psychotropic Substance (Hungary), 78/2022. (XII. 28.) BM rendelet

application(s)

pharmaceutical (small molecule)

format

neat

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Bromazepam EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Legal Information

German
Dieses Produkt fällt unter das Betäubungsmittelgesetz (BtMG). Für eine Bestellung dieses Produktes ist eine Erlaubnis nach § 3 BtMG zwingend erforderlich, es sei denn, es greift eine Ausnahme von der Erlaubnispflicht nach § 4 oder § 26 BtMG.

English
This product is subject to the German Narcotics Act. A permit under Section 3 of the German Narcotics Act is mandatory for ordering this product unless an exemption from the permit requirement under Section 4 or Section 26 of the German Narcotics Act applies.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

监管及禁止进口产品
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Gregory Podilsky et al.
European journal of clinical pharmacology, 65(5), 435-442 (2009-02-04)
To characterize and compare the pharmacokinetic profiles of bromazepam, omeprazole and paracetamol when administered by the oral and nasogastric routes to the same healthy cohort of volunteers. In a prospective, monocentric, randomized crossover study, eight healthy volunteers received the three
Marlo Cunha et al.
Arquivos de neuro-psiquiatria, 67(2A), 214-218 (2009-06-24)
This study aimed to elucidate cortical mechanisms and to identify the areas where occur such mechanisms due to interaction between bromazepam and motor learning. The sample was composed of 45 healthy subjects randomly distributed in 3 groups: placebo (n=15), bromazepam
S Djezzar et al.
International journal of legal medicine, 123(3), 213-219 (2008-10-18)
Psychoactive substances may be administered without the knowledge of a victim in order to induce incapacitation and thus facilitate criminal actions. The characteristics of the victims and the drugs used in such suspected chemical submissions (CS) were analyzed in 309
Daniel Minc et al.
Neuroscience letters, 469(1), 145-149 (2009-12-01)
The goal of the present study was to explore the dynamics of the gamma band using the coherence of the quantitative electroencephalography (qEEG) in a sensorimotor integration task and the influence of the neuromodulator bromazepam on the band behavior. Our
Laura Wainstein et al.
International clinical psychopharmacology, 26(1), 54-62 (2010-10-01)
France has one of the highest recorded rates of psychotropic use of drugs compared with other European countries, especially for anxiolytics, hypnotics and antidepressants. The aim of this study was to characterize the use of three psychotropic drugs among the
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