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B5133

Brilliant Blue G

≥90% (TLC)

Synonym(s):

Acid blue 90, Coomassie Brilliant Blue G

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About This Item

Empirical Formula (Hill Notation):
C47H48N3NaO7S2
CAS Number:
6104-58-1
Molecular Weight:
854.02
UNSPSC Code:
12171500
Beilstein/REAXYS Number:
5230822
Colour Index Number:
42655
MDL number:
MFCD00078482
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assay

≥90% (TLC)

purified by

recrystallization

composition

Dye content, ≥90% elemental analysis

SMILES string

[Na+].CCOc1ccc(Nc2ccc(cc2)C(\c3ccc(cc3C)N(CC)Cc4cccc(c4)S([O-])(=O)=O)=C5\C=CC(\C=C5C)=[N+](\CC)Cc6cccc(c6)S([O-])(=O)=O)cc1

InChI

1S/C47H49N3O7S2.Na/c1-6-49(31-35-11-9-13-43(29-35)58(51,52)53)40-21-25-45(33(4)27-40)47(37-15-17-38(18-16-37)48-39-19-23-42(24-20-39)57-8-3)46-26-22-41(28-34(46)5)50(7-2)32-36-12-10-14-44(30-36)59(54,55)56;/h9-30H,6-8,31-32H2,1-5H3,(H2,51,52,53,54,55,56);/q;+1/p-1

InChI key

RWVGQQGBQSJDQV-UHFFFAOYSA-M

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Biochem/physiol Actions

P2X7 purinergic receptor antagonist.

Preparation Note

Chromatographically purified

Other Notes

This product has been replaced by B0770-Sigma-Aldrich | Brilliant Blue G pure

Legal Information

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
106K7029
105K7032
084K7021
080K7057
080K7007

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Søren U Nielsen et al.
The Journal of general virology, 89(Pt 10), 2507-2517 (2008-09-18)
Hepatitis C virus (HCV) particles found in vivo are heterogeneous in density and size, but their detailed characterization has been restricted by the low titre of HCV in human serum. Previously, our group has found that HCV circulates in blood
Sungwon Han et al.
Analytical and bioanalytical chemistry, 405(6), 1821-1831 (2012-09-25)
Gel electrophoresis is routinely used to separate and analyse macromolecules in biological systems. Although many of these electrophoretic techniques necessitate the denaturing of the analytes prior to their analysis, blue native polyacrylamide gel electrophoresis (BN-PAGE) permits the investigation of proteins/enzymes
Broc R Wenrich et al.
Analytical biochemistry, 428(2), 93-95 (2012-06-30)
The Bradford assay has been used reliably for decades to quantify protein in solution. The analyte is incubated in acidic solution of Coomassie Blue G-250 dye, during which reversible ionic and nonionic binding interactions form. Bradford assay color yields were
Kei Takayama et al.
Investigative ophthalmology & visual science, 53(11), 7389-7394 (2012-10-04)
We compared the phototoxicity of indocyanine green (ICG) and Brilliant Blue G (BBG) in cultured RPE cells under fluorescent lamp illumination imitating ambient light. Cultured human RPE line cells were stained with ICG or BBG solution at concentrations of clinical
Nicole Sessler et al.
Amino acids, 43(3), 1119-1129 (2012-07-24)
Detailed knowledge of the composition of protein complexes is crucial for the understanding of their structure and function; however, appropriate techniques for compositional analyses of complexes largely rely on elaborate tagging, immunoprecipitation, cross-linking and purification strategies. The proteasome is a
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