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Merck
CN

B5524

Benzydamine hydrochloride

analytical standard

Synonym(s):

1-Benzyl-3-(3-[dimethylamino]propoxy)-1H-indazole

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About This Item

Empirical Formula (Hill Notation):
C19H23N3O · HCl
CAS Number:
132-69-4
Molecular Weight:
345.87
NACRES:
NA.24
PubChem Substance ID:
329773263
UNSPSC Code:
41116107
EC Number:
205-076-0
MDL number:
MFCD00078957

Key Documents

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InChI key

HNNIWKQLJSNAEQ-UHFFFAOYSA-N

InChI

1S/C19H23N3O.ClH/c1-21(2)13-8-14-23-19-17-11-6-7-12-18(17)22(20-19)15-16-9-4-3-5-10-16;/h3-7,9-12H,8,13-15H2,1-2H3;1H

SMILES string

Cl.CN(C)CCCOc1nn(Cc2ccccc2)c3ccccc13

grade

analytical standard

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

storage temp.

2-8°C

Quality Level

200

Gene Information

human ... PTGS1(5742), PTGS2(5743)

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Application

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pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302,H319

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

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Certificates of Analysis (COA)

Lot/Batch Number
0000257025
0000257025
0000254328
0000254328

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S Rossi et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 74(2), 248-254 (2009-10-27)
The aim of the present work was the development of a thermally sensitive mucoadhesive gel based on chitosan derivatives for the treatment of oral mucositis. Trimethyl chitosan (TMC) and methylpyrrolidinone chitosan (MPC) were considered. They were mixed with glycerophosphate (GP)
Takeshi Sawada et al.
Xenobiotica; the fate of foreign compounds in biological systems, 50(5), 526-535 (2019-09-07)
1. Immunodeficient chimeric mice with humanised liver have been useful in predicting total clearance values of drugs in humans. However, their usefulness may currently be limited for specific compounds with interspecies differences.2. In vivo total clearance and in vitro hepatic
F Capolongo et al.
Journal of veterinary pharmacology and therapeutics, 33(4), 341-346 (2010-07-22)
Benzydamine (BZ), a weak base and an indazole derivative with analgesic and antipyretic properties used in human and veterinary medicine, is metabolized in human, rat, cattle and rabbit to a wide range of metabolites. One of the main metabolites, BZ
Koray Soygun et al.
The journal of advanced prosthodontics, 9(3), 200-207 (2017-07-07)
In this study, three bioceramic materials, [IPS Empress CAD (Ivoclar), IPS e.max CAD (Ivoclar), and Lava Ultimate CAD (3M ESPE)] were treated with three commercial mouthrinses [Listerine, Tantum Verde, and Klorhex]; and changes in colour reflectance and surface roughness values
Ali Fuat Erciyas et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 48(10), 2577-2580 (2010-07-06)
In this study, genotoxicity of two mouthwash products (chlorexidin, benzidamine-HCl) were investigated in the Drosophila Wing-Spot Test which makes use of the wing cell markers multiple wing hairs (mwh) and flare (flr) and detects both mitotic recombination and various types
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