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Merck
CN

B5524

Benzydamine hydrochloride

analytical standard

Synonym(s):

1-Benzyl-3-(3-[dimethylamino]propoxy)-1H-indazole

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About This Item

Empirical Formula (Hill Notation):
C19H23N3O · HCl
CAS Number:
132-69-4
Molecular Weight:
345.87
NACRES:
NA.24
PubChem Substance ID:
329773263
UNSPSC Code:
41116107
EC Number:
205-076-0
MDL number:
MFCD00078957

Key Documents

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InChI key

HNNIWKQLJSNAEQ-UHFFFAOYSA-N

InChI

1S/C19H23N3O.ClH/c1-21(2)13-8-14-23-19-17-11-6-7-12-18(17)22(20-19)15-16-9-4-3-5-10-16;/h3-7,9-12H,8,13-15H2,1-2H3;1H

SMILES string

Cl.CN(C)CCCOc1nn(Cc2ccccc2)c3ccccc13

grade

analytical standard

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

storage temp.

2-8°C

Quality Level

200

Gene Information

human ... PTGS1(5742), PTGS2(5743)

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Application

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pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302,H319

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

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Certificates of Analysis (COA)

Lot/Batch Number
0000257025
0000257025
0000254328
0000254328

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S Y Karavana Hizarcioğlu et al.
International journal of oral and maxillofacial surgery, 40(9), 973-978 (2011-05-10)
The aim of this study was to investigate the effect of benzydamine hydrochloride bioadhesive gel on healing of oral mucosal ulceration in an animal model. For in vivo determination of the effects of the bioadhesive gel, 36 rabbits were separated
Yadira X Perez-Paramo et al.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 28(2), 311-320 (2018-11-02)
The major mode of metabolism of nicotine is by hydroxylation via cytochrome P450 (CYP) 2A6, but it can also undergo glucuronidation by UDP-glucuronosyltransferases and oxidation by flavin monooxygenases (FMO). The goal of this study was to examine the potential importance
N R Patil et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 79(5), 1985-1991 (2011-07-01)
Fluorescence quenching of biologically active carboxamide namely (E)-2-(4-chlorobenzylideneamino)-N-(2-chlorophenyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide [ECNCTTC] by aniline and carbon tetrachloride (CCl4) quenchers in different solvents using steady state method and time resolved method using only one solvent has been carried out at room temperature to understand
S Rossi et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 74(2), 248-254 (2009-10-27)
The aim of the present work was the development of a thermally sensitive mucoadhesive gel based on chitosan derivatives for the treatment of oral mucositis. Trimethyl chitosan (TMC) and methylpyrrolidinone chitosan (MPC) were considered. They were mixed with glycerophosphate (GP)
Takeshi Sawada et al.
Xenobiotica; the fate of foreign compounds in biological systems, 50(5), 526-535 (2019-09-07)
1. Immunodeficient chimeric mice with humanised liver have been useful in predicting total clearance values of drugs in humans. However, their usefulness may currently be limited for specific compounds with interspecies differences.2. In vivo total clearance and in vitro hepatic
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