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BCR265

Dibenzo[a,e]fluoranthene

BCR®, certified reference material

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About This Item

Empirical Formula (Hill Notation):
C24H14
CAS Number:
5385-75-1
Molecular Weight:
302.37
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329773799
MDL number:
MFCD00215892
Beilstein/REAXYS Number:
2120920

Key Documents

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InChI

1S/C24H14/c1-3-9-17-15(7-1)13-22-19-11-5-6-12-20(19)23-18-10-4-2-8-16(18)14-21(17)24(22)23/h1-14H

SMILES string

c1ccc-2c(c1)-c3cc4ccccc4c5cc6ccccc6c-2c35

InChI key

JHOWUOKQHJHGMU-UHFFFAOYSA-N

grade

certified reference material

agency

BCR®

manufacturer/tradename

JRC

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

format

neat

storage temp.

2-8°C

Related Categories

Analysis Note

For more information please see:
BCR265

Legal Information

BCR is a registered trademark of European Commission

pictograms

Health hazard
GHS08

signalword

Warning

hcodes

H351

Hazard Classifications

Carc. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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F Zajdela et al.
Carcinogenesis, 8(3), 461-464 (1987-03-01)
Dibenzofluoranthene-12,13-dihydrodiol (DBF-12,13-DHD) is six times more mutagenic in Salmonella TA100 than dibenzofluoranthene-3,4-dihydrodiol (DBF-3,4-DHD). However, these two major dibenzo[a,e]fluoranthene (DBF) proximate metabolites, which are immediate precursors of the corresponding diolepoxides, showed on an equimolar basis nearly identical initiation activities on mouse
O Perin-Roussel et al.
Cancer letters, 36(2), 169-180 (1987-08-01)
The production by dibenzo[a,e]fluoranthene (DBF) of DNA-protein cross-links in cultured mouse fibroblasts is probably mediated by the activation of proximate metabolites of DBF and not by the DBF molecule itself. In order to test this hypothesis, several agents that enhance
Metabolic activation of dibenzo(a,e)fluoranthene, a nonalternant carcinogenic polycyclic hydrocarbon, in liver homogenates.
O Perin-Roussel et al.
Cancer research, 40(5), 1742-1749 (1980-05-01)
O Périn-Roussel et al.
Carcinogenesis, 13(4), 723-725 (1992-04-01)
Quantitative and qualitative changes in the inhibition of DNA adduct formation in the presence of increasing concentrations of norharman (NH) were investigated in vivo in mouse fibroblasts treated with dibenzo[a,e]fluoranthene (DBF), a potent carcinogen in mice. The nuclease P1 modification
O Perin-Roussel et al.
Chemico-biological interactions, 37(1-2), 109-122 (1981-10-01)
The effects of norharman (NH) on the metabolism of dibenzo[a,e]-fluoranthene (DBF) and on its fixation on DNA, RNA and proteins have been studied in vitro by incubation with S-9 and microsomes from rats and mice. NH causes a decrease of
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