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BCR266

7H-Dibenzo[c,g]carbazole

BCR®, certified reference material

Synonym(s):

3,4,5,6-Dibenzocarbazole

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About This Item

Empirical Formula (Hill Notation):
C20H13N
CAS Number:
194-59-2
Molecular Weight:
267.32
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329773800
MDL number:
MFCD00215941
Beilstein/REAXYS Number:
213015

Key Documents

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Product Name

7H-Dibenzo[c,g]carbazole, BCR®, certified reference material

InChI key

STJXCDGCXVZHDU-UHFFFAOYSA-N

SMILES string

[H]n1c2ccc3ccccc3c2c4c1ccc5ccccc45

InChI

1S/C20H13N/c1-3-7-15-13(5-1)9-11-17-19(15)20-16-8-4-2-6-14(16)10-12-18(20)21-17/h1-12,21H

grade

certified reference material

agency

BCR®

manufacturer/tradename

JRC

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

format

neat

storage temp.

2-8°C

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Analysis Note

For more information please see:
BCR266

Legal Information

BCR is a registered trademark of European Commission

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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Glenn Talaska et al.
Toxicology letters, 162(2-3), 246-249 (2005-11-01)
Studies of the impact of phase 1 enzyme polymorphisms on genetic damage have yielded mixed results. We studied how genetic damage would be altered when specific genes were ablated under low dose conditions. Knockouts (KO) were generated from c57bl6/J mice
Zuzana Valovicová et al.
Mutation research, 665(1-2), 51-60 (2009-05-12)
Liver progenitor (oval) cells are a potential target cell population for hepatocarcinogens. Our recent study showed that the liver carcinogens 7H-dibenzo[c,g]carbazole (DBC) and 5,9-dimethyldibenzo[c,g]carbazole (DiMeDBC), but not the sarcomagen N-methyldibenzo[c,g]carbazole (N-MeDBC), induced several cellular events associated with tumor promotion in
O Dorchies et al.
Toxicologic pathology, 29(5), 528-534 (2001-11-07)
The purpose of this work was to investigate the administration of very low but repeated doses of a genotoxic carcinogen and an eventual correlation with cellular DNA synthesis. The compound 7H-dibenzo[c,g]carbazole is a genotoxic carcinogen in the mouse liver and
G Ericson et al.
Mutation research, 454(1-2), 11-20 (2000-10-18)
The time-course and dose dependent formation of DNA adducts in juvenile northern pike (Esox lucius) following a single exposure to a mixture of benzo[a]pyrene (BaP), benzo[k]fluoranthene (BkF) and 7H-dibenzo[c,g]carbazole (DBC) were investigated by use of the (32)P-postlabelling assay. A complex
Alena Gábelová et al.
Environmental and molecular mutagenesis, 52(8), 636-645 (2011-08-03)
The goal of this study was to investigate the genotoxicity of 7H-dibenzo[c,g]carbazole (DBC), a ubiquitous environmental pollutant, and its methyl derivatives, 5,9-dimethylDBC (DiMeDBC), a strict hepatocarcinogen, and N-methylDBC (N-MeDBC), a specific sarcomagen in human hepatoma HepG2 cells, and to infer
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