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Merck
CN

C1609

5(6)-Carboxyfluorescein N-hydroxysuccinimide ester

≥90% (HPLC)

Synonym(s):

5(6)-FAM SE, FLUOS

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About This Item

Empirical Formula (Hill Notation):
C25H15NO9
CAS Number:
117548-22-8
Molecular Weight:
473.39
UNSPSC Code:
12352200
MDL number:
MFCD04119713

Key Documents

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InChI key

YVTPVJDECOUTJW-UHFFFAOYSA-N

InChI

1S/2C25H15NO9/c27-13-2-5-16-19(10-13)34-20-11-14(28)3-6-17(20)23(16)18-9-12(1-4-15(18)24(31)32)25(33)35-26-21(29)7-8-22(26)30;27-12-4-6-14-18(10-12)34-19-11-13(28)5-7-15(19)22(14)23-16(24(31)32)2-1-3-17(23)25(33)35-26-20(29)8-9-21(26)30/h1-6,9-11,27H,7-8H2,(H,31,32);1-7,10-11,27H,8-9H2,(H,31,32)

SMILES string

OC(=O)c1ccc(cc1C2=C3C=CC(=O)C=C3Oc4cc(O)ccc24)C(=O)ON5C(=O)CCC5=O.OC(=O)c6cccc(C(=O)ON7C(=O)CCC7=O)c6C8=C9C=CC(=O)C=C9Oc%10cc(O)ccc8%10

assay

≥90% (HPLC)

storage temp.

−20°C

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Application

Fluorescent label for primary and secondary amine groups on proteins and other biomolecules.
Has been used to prepare fluorescent derivatives of tubulin and for the preparation of a phenytoin tracer for the determination of this drug in serum and plasma by fluorescence polarization immunoassay (FPIA)
Reacts with primary and secondary amine groups on proteins and other biomolecules.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
BCBD1701V
BCBF3178V
1374458
1367487
1341338

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Yulia N Demchenko et al.
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Qin-Ying Liu et al.
Marine drugs, 13(8), 4733-4753 (2015-08-13)
Penicitrinine A, a novel alkaloid with a unique spiro skeleton, was isolated from a marine-derived fungus Penicillium citrinum. In this study, the isolation, structure and biosynthetic pathway elucidation of the new compound were described. This new compound showed anti-proliferative activity
Chao He et al.
DNA and cell biology, 34(11), 677-683 (2015-08-15)
Large intergenic long noncoding RNA p21 (lincRNA-p21) has recently shown to play an important role in biological functions. However, the biological role of lincRNA-p21 in vascular endothelial cells remains unclear. In the present study, we investigated the role of lincRNA-p21
J Cai et al.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 16(7), 650-659 (2013-11-13)
5-Fluorouracil (5-Fu) is a commonly used chemotherapeutic agent in clinical care of breast cancer patients. However, the mechanism of how the 5-Fu works is complex and still largely unknown. The objective of this study was to understand the mechanism further
Yanyong Sun et al.
Neuropathology and applied neurobiology, 41(3), 347-370 (2014-03-13)
Insufficient oligodendroglial differentiation of oligodendroglial progenitor cells (OPCs) is suggested to be responsible for remyelination failure and astroglial scar formation in Theiler's murine encephalomyelitis (TME). The aim of the present study is to identify molecular key regulators of OPC differentiation
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