C2040
Cloperastine hydrochloride
analytical standard
Synonym(s):
4-Chlorobenzhydryl 2-(1-piperidyl)ethyl ether
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About This Item
Empirical Formula (Hill Notation):
C20H24ClNO · HCl
CAS Number:
Molecular Weight:
366.32
UNSPSC Code:
41116107
PubChem Substance ID:
EC Number:
239-067-8
MDL number:
InChI key
UNPLRYRWJLTVAE-UHFFFAOYSA-N
InChI
1S/C20H24ClNO.ClH/c21-19-11-9-18(10-12-19)20(17-7-3-1-4-8-17)23-16-15-22-13-5-2-6-14-22;/h1,3-4,7-12,20H,2,5-6,13-16H2;1H
SMILES string
Cl.Clc1ccc(cc1)C(OCCN2CCCCC2)c3ccccc3
grade
analytical standard
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
veterinary
format
neat
Quality Level
Application
Cloperastine hydrochloride may be used as an analytical standard for the quantification of cloperastine in biological samples using liquid chromatography coupled to tandem mass spectrometry.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
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[Effect of cloperastine on muco-ciliary clearance].
D Olivieri et al.
Archivio Monaldi per la tisiologia e le malattie dell'apparato respiratorio, 38(5-6), 219-223 (1983-09-01)
Hao Li et al.
Journal of pharmaceutical and biomedical analysis, 51(3), 716-722 (2009-11-03)
A rapid and sensitive method based on liquid chromatography-tandem mass spectrometry (LC-MS/MS) for the simultaneous quantitation of paracetamol, caffeine, pseudoephedrine, chlorpheniramine and cloperastine in human plasma has been developed and validated. After sample preparation by liquid-liquid extraction, the analytes and
Yukoh Sakata et al.
International journal of pharmaceutics, 335(1-2), 12-19 (2006-11-23)
Tablets containing both paracetamol (PM) and cloperastine hydrochloride (CLH) in a combination formulation prepared by standard vertical granulation technology were found to have altered pharmaceutical properties. The hardness and disintegration time of tablets containing both PM and CLH gradually increased
Gen Yamamoto et al.
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 131(4), 523-532 (2011-04-07)
Clinically, both overactive bladder (OAB) and dysuria are known to occur in patients with cerebral infarction (CI). A few anticholinergic drugs are used to treat OAB in such patients, although the effect is not satisfactory. On the other hand, little
[Cloperastine fendizoate in the treatment of cough-producing diseases in pediatrics].
L Scotti et al.
Minerva pediatrica, 40(5), 283-286 (1988-05-01)
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