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Merck
CN

C8278

Carbinoxamine maleate salt

analytical standard

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About This Item

Empirical Formula (Hill Notation):
C16H19ClN2O · C4H4O4
CAS Number:
3505-38-2
Molecular Weight:
406.86
NACRES:
NA.24
PubChem Substance ID:
329775166
UNSPSC Code:
41116107
EC Number:
222-498-0
MDL number:
MFCD00082461

Key Documents

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Product Name

Carbinoxamine maleate salt, analytical standard

InChI key

GVNWHCVWDRNXAZ-BTJKTKAUSA-N

InChI

1S/C16H19ClN2O.C4H4O4/c1-19(2)11-12-20-16(15-5-3-4-10-18-15)13-6-8-14(17)9-7-13;5-3(6)1-2-4(7)8/h3-10,16H,11-12H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

SMILES string

OC(=O)\C=C/C(O)=O.CN(C)CCOC(c1ccc(Cl)cc1)c2ccccn2

grade

analytical standard

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

Quality Level

100

Gene Information

human ... HRH1(3269)

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

pictograms

Skull and crossbones
GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
MKCT0447
MKCN7088
MKCL3543
MKCF1527
MKBW2297V

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A Chakrabarti et al.
International journal of clinical pharmacology, therapy, and toxicology, 25(6), 310-312 (1987-06-01)
The efficacy and safety of a new antitussive expectorant drug hexapneumine was compared with that of an already marketed and functionally related clistine in a double-blind, randomized, parallel design clinical trial. A total of 100 patients with cough associated with
Hieronim Jakubowski
Chemistry (Weinheim an der Bergstrasse, Germany), 12(31), 8039-8043 (2006-09-05)
Chemical reactivity of homocysteine thiolactone (HTL) has been implicated in cardiovascular disease. Owing to its aminoacyl-thioester character, HTL undergoes facile electrophilic and nucleophilic reactions at its amino and activated-carboxyl group, respectively. To gain insight into the mechanism of the reactions
D J Hoffman et al.
Journal of pharmaceutical sciences, 72(11), 1342-1344 (1983-11-01)
Capillary gas chromatography using an open tubular fused silica column and NP-FID was applied to the simultaneous analysis of the antihistamine, carbinoxamine, and the antitussive, hydrocodone, in human serum. Carbinoxamine and hydrocodone were extracted into methylene chloride-2-propanol (9:1) under alkaline
A A Ramadan et al.
Analytical biochemistry, 353(1), 133-137 (2006-04-01)
A simple and sensitive spectrophotometric method was developed for the determination of carbinoxamine maleate in pharmaceutical formulations. The method is based on the formation of a ternary complex, extractable with chloroform, between copper(II), eosin, and carbinoxamine maleate. The absorption spectra
V R Chistiakova et al.
Vestnik otorinolaringologii, (3)(3), 88-91 (2012-09-07)
The objective of the present study was to estimate the therapeutic efficacy of rinopront used to treat inflammatory diseases of the nasopharynx in the children. The study included 32 patients at the age between 12 and 14 years presenting with
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