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Merck
CN

CND5146

Diazolidinyl urea

≥95%

Synonym(s):

1-[1,3-Bis(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]-1,3-bis(hydroxymethyl)urea, Diazolidinylurea, N-Hydroxymethyl-N-[1,3-di(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]-N′-hydroxymethylurea, N-[1,3-Bis(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl]-N,N′-bis(hydroxymethyl)urea

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About This Item

Empirical Formula (Hill Notation):
C8H14N4O7
CAS Number:
78491-02-8
Molecular Weight:
278.22
NACRES:
NA.22
PubChem Substance ID:
57654106
UNSPSC Code:
12352100
MDL number:
MFCD03547942

Key Documents

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Product Name

Diazolidinyl urea, ≥95%

InChI

1S/C8H14N4O7/c13-1-9-7(18)10(2-14)5-6(17)12(4-16)8(19)11(5)3-15/h5,13-16H,1-4H2,(H,9,18)

SMILES string

OCNC(=O)N(CO)C1N(CO)C(=O)N(CO)C1=O

InChI key

SOROIESOUPGGFO-UHFFFAOYSA-N

assay

≥95%

form

solid

storage temp.

2-8°C

Quality Level

200

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Application

  1. Impact of cosmetic preservatives on skin cells: A study examined the effects of various cosmetic preservatives, including Diazolidinyl Urea, on healthy human skin cells, highlighting the cellular responses and potential implications for skin health (Głaz et al., 2023).
  2. Formaldehyde releasers in personal care: An extensive clinical review discussed allergic contact dermatitis caused by formaldehyde and formaldehyde releasers such as Diazolidinyl Urea, providing insights into allergic reactions and safety concerns in dermatological practice (Goossens and Aerts, 2022).
  3. Carcinogenic potential of cosmetic ingredients: Research on potential carcinogens in makeup cosmetics included Diazolidinyl Urea, emphasizing the safety and regulatory aspects concerning its use in cosmetic formulations (Balwierz et al., 2023).
  4. Patch testing for allergen sensitivity: A study integrated Diazolidinyl Urea in a patch test series to evaluate skin sensitization and allergic reactions in patients, aiding in the assessment of its allergenic potential (Bizjak et al., 2022).

General description

Diazolidinyl urea is urea derivative that is commonly used as a preservative and antimicrobial agent in cosmetics and personal care products.

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Certificates of Analysis (COA)

Lot/Batch Number
WXBF6908V

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