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About This Item
Linear Formula:
ONC6H4N(CH3)2
CAS Number:
Molecular Weight:
150.18
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
EC Number:
205-343-1
MDL number:
Beilstein/REAXYS Number:
607293
Product Name
N,N-Dimethyl-4-nitrosoaniline, ≥97%
Quality Level
assay
≥97%
form
powder or chunks
mp
85-87 °C (lit.)
solubility
ethanol: 5% (green to very dark green)
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
SMILES string
CN(C)c1ccc(cc1)N=O
InChI
1S/C8H10N2O/c1-10(2)8-5-3-7(9-11)4-6-8/h3-6H,1-2H3
InChI key
CMEWLCATCRTSGF-UHFFFAOYSA-N
Application
N,N-Dimethyl-4-nitrosoaniline has been used along with imidazole to detect the formation of singlet oxygen in cells.
Biochem/physiol Actions
N,N-Dimethyl-4-nitrosoaniline is used for the detection of singlet oxygen. Singlet oxygen reacts with imidazole and thereby bleaches N,N-Dimethyl-4-nitrosoaniline via oxidation. Bleaching of N,N-Dimethyl-4-nitrosoaniline is observed as reduction in the absorption at 438nm.
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signalword
Danger
Hazard Classifications
Acute Tox. 3 Oral - Eye Irrit. 2 - Self-heat. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
target_organs
Respiratory system
Storage Class
4.2 - Pyrophoric and self-heating hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Regulatory Information
监管及禁止进口产品
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S Kapur et al.
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I Marie Schreiber et al.
Environmental science & technology, 39(10), 3811-3818 (2005-06-15)
The formation of the potent carcinogen, N-nitrosodimethylamine (NDMA), during chlorine disinfection has caused significant concern among drinking water and wastewater recycling utilities practicing intentional or unintentional chloramination. Previous research modeled NDMA formation as arising from a reaction between monochloramine and
Vassilis L Souliotis et al.
Mutation research, 568(2), 155-170 (2004-11-16)
Following administration to rats of various doses of N-nitrosodimethylamine (NDMA), O(6)-methylguanine (O(6)-meG) was lost from the DNA of four tissues (liver, white blood cells, lymph nodes, bone marrow) over two, sharply demarcated phases with substantially differing repair rates. Repair during
Global Trade Item Number
| SKU | GTIN |
|---|---|
| D172405-100G | 04061832342368 |
| D172405-25G | 04061833560525 |

