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Merck
CN

D2205000

Dimetindene maleate

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

N,N-Dimethyl-2-{3-[(RS)-1-(pyridine-2-yl)ethyl]-1H-inden-2-yl}ethanamin-(Z)-butendioate

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About This Item

Empirical Formula (Hill Notation):
C20H24N2 · C4H4O4
CAS Number:
Molecular Weight:
408.49
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24
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SMILES string

N(CCC1=C(c3c(cccc3)C1)C(C)c2ncccc2)(C)C.OC(=O)\C=C/C(=O)O

InChI

1S/C20H24N2.C4H4O4/c1-15(19-10-6-7-12-21-19)20-17(11-13-22(2)3)14-16-8-4-5-9-18(16)20;5-3(6)1-2-4(7)8/h4-10,12,15H,11,13-14H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

InChI key

SWECWXGUJQLXJF-BTJKTKAUSA-N

grade

pharmaceutical primary standard

API family

dimetindene

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Dimetindene maleate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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[Aso an inspection of the family dog is warrented here].
M F Nentwich et al.
MMW Fortschritte der Medizin, 148(42), 5-5 (2007-07-12)
Anaphylactic shock caused by buffalo's mozzarella cheese.
Sigrid M C Broekaert et al.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 101(1), 105-107 (2008-08-07)
G J Sturm et al.
Allergy, 64(9), 1319-1326 (2009-02-27)
The basophil activation test (BAT) is a widely validated and reliable tool especially for the diagnosis of hymenoptera venom allergy. Nevertheless, several pitfalls have to be considered and outcomes may differ because of diverse in-house protocols and commercially available kits.
Christos Kosmas et al.
Medical science monitor : international medical journal of experimental and clinical research, 12(11), CR462-CR466 (2006-10-31)
Many investigations have focused on optimal doses/schedules since regulatory agency approval of paclitaxel (Taxol). Paclitaxel is generally administered at doses of 175-225 mg/m2 over 3 hours or 135-175 mg/m2 over 24 hours, every 3 weeks. The purpose of this study
C Dopfer et al.
Klinische Padiatrie, 222(7), 460-461 (2010-09-11)
We report a case of acute hemorrhagic edema in a 10-year-old girl caused by adder bite. Therapy consisted of analgesics, antihistamines, corticosteroids. Antivenum serum was applied in a single dose due to severe spreading of the edema. The patient recovered

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