H3393
Heparin sodium salt from porcine intestinal mucosa
Grade I-A, ≥180 USP units/mg
Synonym(s):
Sodium heparin
biological source
Porcine intestinal mucosa
Quality Level
type
Grade I-A
form
powder
specific activity
≥180 USP units/mg
color
beige
useful pH range
5.0 - 7.5
solubility
H2O: 50 mg/mL, clear, colorless to faintly yellow
application(s)
clinical research
diagnostic assay manufacturing
life science and biopharma
storage temp.
room temp
SMILES string
[Na+].[S](=O)(=O)(NC1C(OC(C(C1O[S](=O)(=O)O)OC4OC(C(C(C4O[S](=O)(=O)O)O)O)C(=O)O)CO)OC2C(OC(C(C2O)O[S](=O)(=O)O)OC3C(OC(C(C3O)NC(=O)C)O)CO[S](=O)(=O)O)C(=O)O)O
InChI key
JRTRSJGZMRQDHI-UHFFFAOYSA-N
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General description
Application
- to check the effect of heparin on FGF21 (fibroblast growth factor 21) signaling.
- in immunostaining of mice brain sections
- to quantify white blood cells and red blood cells in Sparus aurata blood samples
- in anticoagulation and severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) inhibition assay
Biochem/physiol Actions
Heparin is synthesized in mast cells and mediators such as histamine and is associated with allergy and inflammatory activity. Heparin shows therapeutic effects against venous thrombosis and pulmonary embolism, helps in preventing re-thrombosis post thrombolysis, and manages arterial thrombosis in patients who suffer from acute myocardial infarction. Heparin shows anti-inflammatory action in many inflammatory conditions such as burns, bronchial asthma, and ulcerative colitis.
Other Notes
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
Regulatory Information
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Certificates of Analysis (COA)
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What is the molecular weight of Heparin sodium salt?
Heparin is a mixture of polyanion chains having molecular weights ranging from 6,000 to 30,000 Daltons, with most chains in the range of 17,000 to 19,000 Daltons.
How much Heparin sodium salt, is used to prevent coagulation?
We suggest using 20 to 50 units per mL of blood.
What is the best way to sterilize Heparin sodium salt?
Although solutions may be autoclaved at 121 °C for 5 to 10 minutes, we generally recommend sterile filtration. This is because prolonged autoclaving may have an effect on its activity.
What concentration of Heparin sodium salt, can I use to inhibit RNAse activity?
Heparin has been used at concentrations ranging from 100 to 500 μg/mL. This has been reported in the J. Biol. Chem., 248, 2095 (1973).
Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
How do I find price and availability?
There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote. USA customers: 1-800-325-3010 or view local office numbers.
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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