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Merck
CN

H9003

Hydroquinone

ReagentPlus®, ≥99%

Synonym(s):

1,4-Benzenediol, 1,4-Dihydroxybenzene, HQ

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About This Item

Linear Formula:
C6H4-1,4-(OH)2
CAS Number:
123-31-9
Molecular Weight:
110.11
Beilstein:
605970
EC Number:
204-617-8
MDL number:
MFCD00002339
UNSPSC Code:
12352005
PubChem Substance ID:
57654278
NACRES:
NA.77

Key Documents

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biological source

synthetic

Quality Level

200

vapor density

3.81 (vs air)

vapor pressure

1 mmHg ( 132 °C)

product line

ReagentPlus®

Assay

≥99%

form

powder

autoignition temp.

930 °F

bp

285 °C (lit.)

mp

172-175 °C (lit.)

solubility

water: 50 mg/mL, clear

SMILES string

Oc1ccc(O)cc1

InChI

1S/C6H6O2/c7-5-1-2-6(8)4-3-5/h1-4,7-8H

InChI key

QIGBRXMKCJKVMJ-UHFFFAOYSA-N

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General description

Hydroquinone is a phenolic compound, which is naturally found in coffee, tea and wine. It is used in photographic, chemical and cosmetic industries. Hydroquinone is used as a skin lightening agent. It is topically applied to treat melisma, freckles and senile lentigines. Hydroquinone is linked to exogenous ochronosis, dermatitis and skin irritation. It inhibits melanogenesis.

Application

Hydroquinone has been used as reagent for the conversion of DNA by sodium bisulfite. It has also been used as a chemical in Timm′s staining.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Eye Dam. 1 - Muta. 2 - Skin Sens. 1B

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

329.0 °F - closed cup

Flash Point(C)

165 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

危险化学品
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Certificates of Analysis (COA)

Lot/Batch Number
0000507663
0000507663
0000499344
0000499344
0000503712

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Topical use of hydroquinone as a depigmenting agent
Arndt KA and Fitzpatrick TB
JAMA : The Journal of the American Medical Association, 194(9), 965-967 (1965)
Xenograft of human umbilical mesenchymal stem cells from Wharton?s jelly as a potential therapy for rat pilocarpine-induced epilepsy
Huang PY, et al.
Brain, behavior, and immunity, 54, 45-58 (2016)
Handbook of Cosmetic Science and Technology (2005)
CDH1 promoter methylation correlates with decreased gene expression and poor prognosis in patients with breast cancer
Liu J, et al.
Oncology Letters, 11(4), 2635-2643 (2016)
Procedures in Cosmetic Dermatology Series: Cosmeceuticals E-Book (2008)
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