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Merck
CN

L0399905

Levocarnitine impurity A

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

(E/Z)-4-(Trimethylammonio)but-2-enoate

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About This Item

Empirical Formula (Hill Notation):
C7H13NO2
CAS Number:
927-89-9
Molecular Weight:
143.18
UNSPSC Code:
41116107
NACRES:
NA.24

Key Documents

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grade

pharmaceutical primary standard

API family

levocarnitine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

[N+](C\C=C\C(=O)[O-])(C)(C)C

InChI

1S/C7H13NO2/c1-8(2,3)6-4-5-7(9)10/h4-5H,6H2,1-3H3/b5-4+

InChI key

GUYHPGUANSLONG-SNAWJCMRSA-N

Related Categories

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Levocarnitine impurity A EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H319

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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[Metabolism of L-carnitine in enterobacteria].
H Seim et al.
Zeitschrift fur allgemeine Mikrobiologie, 20(9), 591-594 (1980-01-01)
M Cánovas et al.
Biotechnology and bioengineering, 96(4), 722-737 (2006-08-09)
The aim was to understand how interaction of the central carbon and the secondary carnitine metabolisms is affected under salt stress and its effect on the production of L-carnitine by Escherichia coli. The biotransformation of crotonobetaine into L-carnitine by resting
[Reduction of L-carnitine to gamma-butyrobetaine by Escherichia coli].
H Seim et al.
Zeitschrift fur allgemeine Mikrobiologie, 19(10), 753-758 (1979-01-01)
T Elssner et al.
Biochemistry, 39(35), 10761-10769 (2000-09-09)
A still unknown low-molecular-mass cofactor essential for the activity of carnitine-metabolizing enzymes (e.g., L-carnitine dehydratase, crotonobetaine reductase) from E. coli has been purified to homogeneity from a cell-free extract of E. coli O44K74. The purity of the cofactor was confirmed
Manuel Cánovas et al.
Journal of basic microbiology, 43(4), 259-268 (2003-07-23)
The biotransformation of crotonobetaine and D(+)-carnitine into L(-)-carnitine is affected by salt stress in the resting cells of E. coli O44 K74 and the transformed E. coli K38 pT7-5KE32. A yield of 65 and 80% of L(-)-carnitine, respectively, were obtained
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