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About This Item
Linear Formula:
HOC6H4CO2CH3
CAS Number:
Molecular Weight:
152.15
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
509801
Product Name
Methyl parahydroxybenzoate, European Pharmacopoeia (EP) Reference Standard
InChI
1S/C8H8O3/c1-11-8(10)6-2-4-7(9)5-3-6/h2-5,9H,1H3
SMILES string
COC(=O)c1ccc(O)cc1
InChI key
LXCFILQKKLGQFO-UHFFFAOYSA-N
grade
pharmaceutical primary standard
API family
parabens
manufacturer/tradename
EDQM
mp
125-128 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
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Application
This European Pharmacopoeia reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia. Their suitability for any other use is not guaranteed and is the sole responsibility of the user. This standard is not intended for human or animal use.
Established for use according to European Pharmacopoeia for the preparation of the below-given solutions:
Established for use according to European Pharmacopoeia for the preparation of the below-given solutions:
- Reference solutions (a) and (b) in the identification, testing for related substances, and assay of methyl parahydroxybenzoate and sodium methyl parahydroxybenzoate, according to the monographs 0409 and 1262
- Reference solution (c) for the testing of related substances in nifuroxazide using liquid chromatography (2.2.29), according to the monograph 1999
- Reference solution (b) in the identification of sodium ethyl parahydroxybenzoate using thin-layer chromatography (General text 2.2.27), according to the monograph 2134
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, has been developed and issued under the Authority of the Issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.
Other Notes
Sales restrictions may apply.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
hcodes
pcodes
Hazard Classifications
Aquatic Chronic 2
Storage Class
13 - Non Combustible Solids
wgk
WGK 1
flash_point_f
334.4 °F
flash_point_c
168 °C
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Nifuroxazide
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 3363-3364 (2017)
Methyl parahydroxybenzoate
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 6180-6181 (2022)
Sodium Ethyl Parahydroxybenzoate
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 3816-3817 (2017)
Sodium Methyl Parahydroxybenzoate
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 3830-3831 (2017)
Ismail I Hewala et al.
Talanta, 88, 623-630 (2012-01-24)
Simple methods for HPTLC peak purity assessment and identification of the HPTLC peaks were presented. The spectrodensitograms - selected at different time intervals across the elution time of the HPTLC peak - were extracted and digital algorithms for manipulating the
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