M2629
3-O-Methylfluorescein phosphate cyclohexylammonium salt
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About This Item
Empirical Formula (Hill Notation):
C21H15O8P · C6H13N
CAS Number:
Molecular Weight:
525.49
UNSPSC Code:
12171500
PubChem Substance ID:
MDL number:
InChI
1S/C21H15O8P.C6H13N/c1-26-12-6-8-16-18(10-12)27-19-11-13(29-30(23,24)25)7-9-17(19)21(16)15-5-3-2-4-14(15)20(22)28-21;7-6-4-2-1-3-5-6/h2-11H,1H3,(H2,23,24,25);6H,1-5,7H2
SMILES string
NC1CCCCC1.COc2ccc3c(Oc4cc(OP(O)(O)=O)ccc4C35OC(=O)c6ccccc56)c2
InChI key
SJPHZMRXIHOGOW-UHFFFAOYSA-N
storage temp.
−20°C
Application
For use in the fluorimetric determination of phosphatase.
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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An automated fluorometric assay for alkaline phosphatase using 3-O-methylfluorescein phosphate.
H D Hill et al.
Analytical biochemistry, 24(1), 9-17 (1968-07-01)
Lok Hang Mak et al.
Methods (San Diego, Calif.), 77-78, 63-68 (2015-03-10)
PTEN (phosphatase and tensin homologue deleted on chromosome 10) is well known as a tumour suppressor. It's PI(3,4,5)P3 lipid phosphatase activity is an important counteracting mechanism in PI 3-kinase (phosphoinositide 3-kinase) signalling. Furthermore, PTEN lies upstream of Akt kinase, a
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