M2649
Melanin from Sepia officinalis
99% purity (TLC), powder
Synonym(s):
Melanin
Product Name
Melanin from Sepia officinalis, 99% (TLC)
Quality Level
Assay
99% (TLC)
form
powder
solubility
hydrogen peroxide: 1 mg/mL, dark brown
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
−20°C
SMILES string
[nH]1c2c3c(c4c5c([nH]c4)c([c]([c](c5c3c1)=O)=O)C)[c]([c](c2C)=O)=O
InChI
1S/C18H10N2O4/c1-5-13-9-7(3-19-13)12-10-8(11(9)17(23)15(5)21)4-20-14(10)6(2)16(22)18(12)24/h3-4,19-20H,1-2H3
InChI key
XUMBMVFBXHLACL-UHFFFAOYSA-N
General description
Melanin is a ubiquitous and prominent pigment responsible for color of skin, hair and eyes. Melanin is classified into eumelanin and pheomelanin. Eumelanin is black to dark brown pigment and is present in black hair and retina of the eye. Pheomelanin is yellow to reddish brown pigment present is red hair and red feathers. Melanins are high molecular weight pigments synthesized from phenolic or indolic precursors and is widely present in animals, plants and microorganisms.
Application
Melanin from Sepia officinalis has been used:
- as a natural pigment for Raman spectroscopy measurements
- in competitive enzyme linked immunosorbent assay (ELISA) for the characterization of phage antibodies
- as an external standard for spectrophotometrically determining the melanin production in B16F10 cells
Biochem/physiol Actions
Melanin scavenges active chemical species and acts as a sunscreen.
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Localization of melanin in conidia of Alternaria alternata using phage display antibodies
Carzaniga R, et al.
Molecular plant-microbe interactions : MPMI, 15(3), 216-224 (2002)
Influence of rosmarinic acid and Salvia officinalis extracts on melanogenesis of B16F10 cells
Oliveira KB, et al.
Revista Brasileira de Farmacognosia, 23(2), 249-258 (2013)
Optical properties of melanin in the skin and skinlike phantoms.
Bashkatov AN
SPIE Proc. (2000)
Bor-Kai Hsiung et al.
The Journal of experimental biology, 218(Pt 22), 3632-3635 (2015-10-10)
Melanin pigments are broadly distributed in nature - from bacteria to fungi to plants and animals. However, many previous attempts to identify melanins in spiders were unsuccessful, suggesting that these otherwise ubiquitous pigments were lost during spider evolution. Yet, spiders
Sunil Kalia et al.
Pigment cell & melanoma research, 31(1), 31-38 (2017-08-15)
Objective measurements of melanin can provide important information for differentiating melanoma from benign pigmented lesions and in assessing pigmentary diseases. Herein, we evaluate near-infrared (NIR) fluorescence as a possible tool to quantify melanin. Various concentrations of in vitro Sepia melanin
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