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M2649

Melanin from Sepia officinalis

99% purity (TLC), powder

Synonym(s):

Melanin

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About This Item

CAS Number:
8049-97-6
UNSPSC Code:
12171500
NACRES:
NA.47
EC Number:
232-473-6
MDL number:
MFCD00131581

Key Documents

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Product Name

Melanin from Sepia officinalis, 99% (TLC)

SMILES string

[nH]1c2c3c(c4c5c([nH]c4)c([c]([c](c5c3c1)=O)=O)C)[c]([c](c2C)=O)=O

InChI

1S/C18H10N2O4/c1-5-13-9-7(3-19-13)12-10-8(11(9)17(23)15(5)21)4-20-14(10)6(2)16(22)18(12)24/h3-4,19-20H,1-2H3

InChI key

XUMBMVFBXHLACL-UHFFFAOYSA-N

assay

99% (TLC)

form

powder

solubility

hydrogen peroxide: 1 mg/mL, dark brown

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

−20°C

Quality Level

200

Related Categories

Application

Melanin from Sepia officinalis has been used:
  • as a natural pigment for Raman spectroscopy measurements
  • in competitive enzyme linked immunosorbent assay (ELISA) for the characterization of phage antibodies
  • as an external standard for spectrophotometrically determining the melanin production in B16F10 cells

Biochem/physiol Actions

Melanin scavenges active chemical species and acts as a sunscreen.

General description

Melanin is a ubiquitous and prominent pigment responsible for color of skin, hair and eyes. Melanin is classified into eumelanin and pheomelanin. Eumelanin is black to dark brown pigment and is present in black hair and retina of the eye. Pheomelanin is yellow to reddish brown pigment present is red hair and red feathers. Melanins are high molecular weight pigments synthesized from phenolic or indolic precursors and is widely present in animals, plants and microorganisms.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
103H1023
100H0118
099F0746

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Localization of melanin in conidia of Alternaria alternata using phage display antibodies
Carzaniga R, et al.
Molecular plant-microbe interactions : MPMI, 15(3), 216-224 (2002)
Melanogenesis in the ink gland of Sepia officinalis.
Palumbo A
Pigment Cell Research / Sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society, 16, 517-517 (2003)
Bor-Kai Hsiung et al.
The Journal of experimental biology, 218(Pt 22), 3632-3635 (2015-10-10)
Melanin pigments are broadly distributed in nature - from bacteria to fungi to plants and animals. However, many previous attempts to identify melanins in spiders were unsuccessful, suggesting that these otherwise ubiquitous pigments were lost during spider evolution. Yet, spiders
Detection of antibodies against Paracoccidioides brasiliensis melanin in in vitro and in vivo studies during infection.
Uran ME
Clinical and Vaccine Immunology : CVI, 18, 1680-1680 (2011)
Sunil Kalia et al.
Pigment cell & melanoma research, 31(1), 31-38 (2017-08-15)
Objective measurements of melanin can provide important information for differentiating melanoma from benign pigmented lesions and in assessing pigmentary diseases. Herein, we evaluate near-infrared (NIR) fluorescence as a possible tool to quantify melanin. Various concentrations of in vitro Sepia melanin
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