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Merck
CN

M9625

L-Methionine

≥98% (HPLC)

Synonym(s):

(S)-2-Amino-4-(methylmercapto)butyric acid, L-2-Amino-4-(methylthio)butanoic acid

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About This Item

Linear Formula:
CH3SCH2CH2CH(NH2)CO2H
CAS Number:
63-68-3
Molecular Weight:
149.21
Beilstein:
1722294
EC Number:
200-562-9
MDL number:
MFCD00063097
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
24897343
NACRES:
NA.26

Key Documents

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Product Name

L-Methionine, reagent grade, ≥98% (HPLC)

grade

reagent grade

Quality Level

200

Assay

≥98% (HPLC)

form

powder

color

white

mp

284 °C (dec.) (lit.)

application(s)

detection

SMILES string

CSCC[C@H](N)C(O)=O

InChI

1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1

InChI key

FFEARJCKVFRZRR-BYPYZUCNSA-N

Gene Information

rat ... Ggt1(116568)

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Application

L-Methionine has been used in chloramine assay and malonaldehyde assay. It has also been used as a standard in methionine assay.

Biochem/physiol Actions

L-Methionine serves as precursor for transmethylation and transsulphuration. Methionine adenosylation results in the formation of S-adenosyl-L-methionine (SAM). SAM serves as a methyl donor to a number of substances. This methylation is significantly associated with the immune system functioning. Thus, SAM deficiency causes severe combined immunodeficiencies. L-Methionine′s metabolic product, glutathione, is known to regulate immune response and has antiviral action.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000480700
0000480700
0000499686
0000499686
0000494305

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Hypochlorite scavenging activity of hydroxycinnamic acids evaluated by a rapid microplate method based on the measurement of chloramines.
Firuzi O
The Journal of Pharmacy and Pharmacology, 55(7), 1021-1027 (2003)
The effects of processing methods on the levels of lysine, methionine and the general acceptability of ogi processed using starter cultures
O.D.Teniola and S.A.Odunfa
International Journal of Food Microbiology, 63(1), 1-9 (2001)
L-methionine as immune supportive supplement: a clinical evaluation
R. Van BrummelenD. du Toit
Amino Acids (2006)
B Almé et al.
Journal of lipid research, 18(3), 339-362 (1977-05-01)
A method is described for quantitative analysis of bile acids in urine. Urine is acidified and bile acids are extracted on an Amberlite XAD-2 column. Bile salts are converted to acids on an Amberlyst A-15 column and are separated into
Ronald O Ball et al.
The Journal of nutrition, 136(6 Suppl), 1682S-1693S (2006-05-17)
Sulfur amino acid metabolism has been receiving increased attention because of the link to chronic diseases such as cardiovascular disease, Alzheimer's disease, and diabetes. In addition, the role of cysteine and optimal intakes for physiological substrates such as glutathione are
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