M9813
MTSEA Biotin-X
≥95% (TLC)
Synonym(s):
2-((6-((Biotinoyl)amino)hexanoyl)amino)ethyl methanethiosulfonate, MTSEA-Biotincap
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About This Item
Empirical Formula (Hill Notation):
C19H34N4O5S3
Molecular Weight:
494.69
UNSPSC Code:
12171500
MDL number:
InChI key
PXMZUZLKVZKKHK-MPGHIAIKSA-N
InChI
1S/C19H34N4O5S3/c1-31(27,28)30-12-11-21-17(25)8-3-2-6-10-20-16(24)9-5-4-7-15-18-14(13-29-15)22-19(26)23-18/h14-15,18H,2-13H2,1H3,(H,20,24)(H,21,25)(H2,22,23,26)/t14-,15-,18-/m0/s1
SMILES string
CS(=O)(=O)SCCNC(=O)CCCCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12
assay
≥95% (TLC)
color
white
solubility
DMF: >10 mg/mL, DMSO: >10 mg/mL
storage temp.
−20°C
Biochem/physiol Actions
Thiol-reactive reagent for labeling proteins at cysteine residues to study structure and function.
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D A Wagner et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 21(1), 67-74 (2001-01-11)
Photo-affinity labeling and mutagenesis studies have identified several amino acids that may contribute to the ligand binding domains of ligand-gated ion channels. These types of studies, however, only generate a one-dimensional, static description of binding site structure. In this study
M Traebert et al.
The Journal of membrane biology, 180(1), 83-90 (2001-04-04)
We have combined a functional assay, surface labeling and immunocytochemical methods to compare total and surface-exposed renal type IIa Na+/Pi cotransporter protein. The wild-type type cotransporter (NaPi-IIa) and its functionally comparable cysteine mutant S460C were expressed in Xenopus oocytes. S460C
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