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Merck
CN

M9813

Sigma-Aldrich

MTSEA Biotin-X

≥95% (TLC)

Synonym(s):

2-((6-((Biotinoyl)amino)hexanoyl)amino)ethyl methanethiosulfonate, MTSEA-Biotincap

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About This Item

Empirical Formula (Hill Notation):
C19H34N4O5S3
Molecular Weight:
494.69
MDL number:
MFCD03453615
UNSPSC Code:
12171500

Key Documents

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Assay

≥95% (TLC)

color

white

solubility

DMF: >10 mg/mL
DMSO: >10 mg/mL

storage temp.

−20°C

SMILES string

CS(=O)(=O)SCCNC(=O)CCCCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12

InChI

1S/C19H34N4O5S3/c1-31(27,28)30-12-11-21-17(25)8-3-2-6-10-20-16(24)9-5-4-7-15-18-14(13-29-15)22-19(26)23-18/h14-15,18H,2-13H2,1H3,(H,20,24)(H,21,25)(H2,22,23,26)/t14-,15-,18-/m0/s1

InChI key

PXMZUZLKVZKKHK-MPGHIAIKSA-N

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Biochem/physiol Actions

Thiol-reactive reagent for labeling proteins at cysteine residues to study structure and function.

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Certificates of Analysis (COA)

Lot/Batch Number
045K0929
081K1227

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D A Wagner et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 21(1), 67-74 (2001-01-11)
Photo-affinity labeling and mutagenesis studies have identified several amino acids that may contribute to the ligand binding domains of ligand-gated ion channels. These types of studies, however, only generate a one-dimensional, static description of binding site structure. In this study
M Traebert et al.
The Journal of membrane biology, 180(1), 83-90 (2001-04-04)
We have combined a functional assay, surface labeling and immunocytochemical methods to compare total and surface-exposed renal type IIa Na+/Pi cotransporter protein. The wild-type type cotransporter (NaPi-IIa) and its functionally comparable cysteine mutant S460C were expressed in Xenopus oocytes. S460C

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