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Merck
CN

N0395

Nifenazone

analytical standard

Synonym(s):

1,5-Dimethyl-4-nicotinamido-2-phenyl-3-pyrazolone

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About This Item

Empirical Formula (Hill Notation):
C17H16N4O2
CAS Number:
2139-47-1
Molecular Weight:
308.33
UNSPSC Code:
41116107
PubChem Substance ID:
329818431
EC Number:
218-387-1
MDL number:
MFCD00214069

Key Documents

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InChI key

BRZANEXCSZCZCI-UHFFFAOYSA-N

InChI

1S/C17H16N4O2/c1-12-15(19-16(22)13-7-6-10-18-11-13)17(23)21(20(12)2)14-8-4-3-5-9-14/h3-11H,1-2H3,(H,19,22)

SMILES string

CN1N(c2ccccc2)C(=O)C(NC(=O)c3cccnc3)=C1C

grade

analytical standard

assay

>98%

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

storage temp.

2-8°C

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class

13 - Non Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

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[Nifenazone, biotransformation in humans].
K H Beyer et al.
Archiv der Pharmazie, 318(9), 855-863 (1985-09-01)
Anna Maria Santoro et al.
ChemMedChem, 15(3), 302-316 (2019-12-05)
Proteasome malfunction parallels abnormal amyloid accumulation in Alzheimer's Disease (AD). Here we scrutinize a small library of pyrazolones by assaying their ability to enhance proteasome activity and protect neuronal cells from amyloid toxicity. Tube tests evidenced that aminopyrine and nifenazone
Timothy M Martin et al.
The journal of gene medicine, 17(1-2), 14-32 (2015-02-11)
Design of efficient nonviral gene delivery systems is limited as a result of the rudimentary understanding of the specific molecules and processes that facilitate DNA transfer. Lipoplexes formed with Lipofectamine 2000 (LF2000) and plasmid-encoding green fluorescent protein (GFP) were delivered

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