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Merck
CN

N2880

Neutral Red

practical grade

Synonym(s):

3-Amino-7-dimethylamino-2-methylphenazine hydrochloride, Basic Red 5, Toluylene red

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About This Item

Empirical Formula (Hill Notation):
C15H17ClN4
CAS Number:
553-24-2
Molecular Weight:
288.78
UNSPSC Code:
12171500
EC Number:
209-035-8
Beilstein/REAXYS Number:
3918740
MDL number:
MFCD00012651

Key Documents

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grade

practical grade

composition

Dye content, ~60%

technique(s)

titration: suitable

pH

6.8-8.0, red to yellow

mp

290 °C (dec.) (lit.)

SMILES string

Cl.CN(C)c1ccc2nc3cc(C)c(N)cc3nc2c1

InChI

1S/C15H16N4.ClH/c1-9-6-13-15(8-11(9)16)18-14-7-10(19(2)3)4-5-12(14)17-13;/h4-8H,16H2,1-3H3;1H

InChI key

PGSADBUBUOPOJS-UHFFFAOYSA-N

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Application

Useful as an indicator for preparing neutral red paper, and as a biological stain.

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
129H3681
124K1002
093H0640
056H0121
053K11871

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Marina T Siirin et al.
The American journal of tropical medicine and hygiene, 79(6), 955-962 (2008-12-05)
The efficacy of a recombinant subunit West Nile (WN) vaccine candidate was determined in a hamster model of encephalitis. Animals included young, aged, and immunocompromised animals in an effort to simulate key groups at risk of WN virus-induced disease. Groups
Adrivanio Baranoski et al.
Toxicology mechanisms and methods, 25(9), 672-679 (2015-05-15)
The β-glucans (β-G) are polysaccharides produced by various organisms, and sulfation of β-G renders them more soluble. With the objective to assess the effects of sulfated and non-sulfated β-G extracted from Agaricus brasiliensis in MCF-7 cells, assays were used to
Timothy D Harrington et al.
Bioresource technology, 192, 689-695 (2015-06-22)
The aim of this work was to elucidate the mechanism of mediated microbial electrosynthesis via neutral red from an electrode to fermenting Escherichia coli cultures in a bioelectrochemical system. Chemical reduction of NAD(+) by reduced neutral red did not occur
Mary F Fontana et al.
PLoS pathogens, 7(2), e1001289-e1001289 (2011-03-11)
The intracellular bacterial pathogen Legionella pneumophila causes an inflammatory pneumonia called Legionnaires' Disease. For virulence, L. pneumophila requires a Dot/Icm type IV secretion system that translocates bacterial effectors to the host cytosol. L. pneumophila lacking the Dot/Icm system is recognized
Sonia Soloneski et al.
Toxicology in vitro : an international journal published in association with BIBRA, 29(5), 834-844 (2015-03-31)
In vitro effects of the carbamates pirimicarb and zineb and their formulations Aficida® (50% pirimicarb) and Azzurro® (70% zineb), respectively, were evaluated in Chinese hamster ovary (CHO-K1) cells. Whereas the cytokinesis-blocked micronucleus cytome assay was employed to test for genotoxicity

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