O5879
Ornidazole
analytical standard
Synonym(s):
1-(3-Chloro-2-hydroxypropyl)-2-methyl-5-nitroimidazole
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About This Item
Linear Formula:
C7H10N3O3Cl
CAS Number:
Molecular Weight:
219.63
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
grade
analytical standard
Quality Level
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
veterinary
format
neat
SMILES string
Cc1ncc(n1CC(O)CCl)[N+]([O-])=O
InChI
1S/C7H10ClN3O3/c1-5-9-3-7(11(13)14)10(5)4-6(12)2-8/h3,6,12H,2,4H2,1H3
InChI key
IPWKIXLWTCNBKN-UHFFFAOYSA-N
Application
Ornidazole has been used as a standard in the determination of traces of ornidazole in samples of aquaculture tissue using ultra high performance liquid chromatography coupled with mass spectrometry (UHPLC).
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Kriti Shivhare et al.
International journal of biological macromolecules, 106, 775-783 (2017-08-19)
Molecular self-assembly of biodegradable amphiphilic polymers allows rational design of biocompatible nanomaterials for drug delivery. Use of substituted polysaccharides for such applications offers the ease of design and synthesis, and provides higher biofunctionality and biocompatibility to nanomaterials. The present work
Subhash S Vaghani et al.
Carbohydrate research, 347(1), 76-82 (2011-11-22)
In the present study, carboxymethyl chitosan was prepared from chitosan, crosslinked with glutaraldehyde and evaluated in vitro as a potential carrier for colon targeted drug delivery of ornidazole. Ornidazole was incorporated at the time of crosslinking of carboxymethyl chitosan. The
Haozhe Tang et al.
BMC oral health, 17(1), 163-163 (2017-12-30)
We investigated the clinical and radiographic outcomes of autotransplanted teeth over a follow-up period of 2 to 8 years, and summarize the findings of other relevant studies with regard to the primary factors that influence a good prognosis in such patients.
Nathalie Mahé et al.
Journal of pharmaceutical sciences, 100(6), 2258-2266 (2011-01-20)
The solid-state properties of antiprotozoal ternidazole (3-(2-methyl-5-nitroimidazol-1-yl)-propan-1-ol) have been studied. Crystals are triclinic in the temperature interval between 100 and 333 K (melting point) with two different molecular conformations present in the asymmetric unit (Z' = 2) and two of
Marta Dolores Mudry et al.
Mutation research, 721(1), 108-113 (2011-01-25)
The genotoxicity of two nitroimidazole derivatives, ornidazole (ONZ) and metronidazole (MTZ) in the peripheral blood lymphocytes of Cebus libidinosus (CLI) (Primates, Cebidae) was assessed. Endpoints measured included sister chromatid exchange (SCE) frequency, cell proliferation kinetics (CPK), replication index (RI), mitotic
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