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Merck
CN

P3347

Prilocaine hydrochloride

meets USP testing specifications

Synonym(s):

N-(2-Methylphenyl)-2-(propylamino)propanamide hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C13H20N2O · HCl
CAS Number:
1786-81-8
Molecular Weight:
256.77
NACRES:
NA.21
PubChem Substance ID:
24898404
UNSPSC Code:
12352200
EC Number:
217-244-0
MDL number:
MFCD00079279

Key Documents

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InChI key

BJPJNTKRKALCPP-UHFFFAOYSA-N

InChI

1S/C13H20N2O.ClH/c1-4-9-14-11(3)13(16)15-12-8-6-5-7-10(12)2;/h5-8,11,14H,4,9H2,1-3H3,(H,15,16);1H

SMILES string

Cl[H].CCCNC(C)C(=O)Nc1ccccc1C

agency

USP/NF, meets USP testing specifications

form

solid

application(s)

pharmaceutical (small molecule)

Quality Level

200

Gene Information

human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

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flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Storage Class

11 - Combustible Solids

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Certificates of Analysis (COA)

Lot/Batch Number
1417729V
087H1027
1417729
086K1927
076K1046

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Young-Eun Moon et al.
Archives of physical medicine and rehabilitation, 94(5), 919-924 (2012-12-25)
To compare the effects of a vapocoolant spray and an eutectic mixture of local anesthetics (EMLA) cream in reducing pain during needle electromyography examination. Randomized controlled trial. Physical medicine and rehabilitation department of a university hospital. Adults who underwent needle
S Schreiber et al.
European journal of pediatrics, 172(2), 265-268 (2012-10-25)
Venipuncture and intravenous cannulation are the most common painful procedures performed on children. The most widely used topical anesthetic is eutectic mixture of local anesthetics (EMLA). EMLA use is associated with a transient cutaneous vasoconstriction which can make it difficult
Michelle Briggs et al.
The Cochrane database of systematic reviews, 11, CD001177-CD001177 (2012-11-16)
Venous leg ulcers affect up to 1% of people at some time in their lives and are often painful. The main treatments are compression bandages and dressings. Topical treatments to reduce pain during and between dressing changes are sometimes used.
A Chan et al.
Journal of dental research, 91(7 Suppl), 79S-84S (2012-09-21)
This double-blind, randomized, clinical trial investigated the effectiveness and underlying mechanism of neural inhibition of pulsed Nd:YAG laser induction of pulpal analgesia compared with 5% EMLA anesthetic cream. Forty-four paired premolars from 44 orthodontic patients requiring bilateral premolar extraction from
Rebeca M Plank et al.
Journal of pediatric urology, 9(1), e86-e90 (2012-10-30)
We report two cases of newborns who developed marked local edema after application of a eutectic mixture of local anesthetic (EMLA) topical anesthetic cream for neonatal male circumcision (NMC). Although local edema and erythema are known potential side effects of
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