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Merck
CN

P5156

Pyrithioxin dihydrochloride

analytical standard

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About This Item

Empirical Formula (Hill Notation):
C16H20N2O4S2 · 2HCl
CAS Number:
Molecular Weight:
441.39
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
233-178-5
MDL number:
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InChI key

HRZWYHGGJOWGRI-UHFFFAOYSA-N

InChI

1S/C16H20N2O4S2.2ClH/c1-9-15(21)13(5-19)11(3-17-9)7-23-24-8-12-4-18-10(2)16(22)14(12)6-20;;/h3-4,19-22H,5-8H2,1-2H3;2*1H

SMILES string

OC1=C(CO)C(CSSCC2=C(CO)C(O)=C(C)N=C2)=CN=C1C.Cl.Cl

grade

analytical standard

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

vitamins, nutraceuticals, and natural products

format

neat

storage temp.

2-8°C

Quality Level

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Certificates of Analysis (COA)

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Occupational contact dermatitis due to pyritinol.
W Wigger-Alberti et al.
Contact dermatitis, 37(2), 91-92 (1997-08-01)
M K C Nair et al.
Indian pediatrics, 46 Suppl, s37-s42 (2009-05-16)
To evaluate the efficacy of pyritinol in improving the neurodevelopmental outcome at one year of age among term babies with post-asphyxial encephalopathy. Level II Neonatal Nursery and Child Development Centre, Medical College, Thiruvananthapuram. Randomised placebo controlled double blind trial. 108
Guillermina Yanek Jiménez-Andrade et al.
European journal of pharmacology, 590(1-3), 170-176 (2008-07-03)
The purpose of this study was to assess the antinociceptive and antiallodynic effect of pyritinol as well as its possible mechanism of action in diabetic rats. Streptozotocin (50 mg/kg) injection caused hyperglycemia within 1 week. Formalin-evoked flinching was increased in
H Hartmann et al.
Neuropharmacology, 32(2), 119-125 (1993-02-01)
The effect of pyritinol, a commonly used nootropic drug, on receptor properties and function was investigated in different neuronal systems, possibly associated with age-related decline in brain function. Chronic treatment (15 days) of aged (22 months) female NMRI mice with
W D Heiss et al.
Dementia (Basel, Switzerland), 5(2), 88-98 (1994-03-01)
70 patients with probable Alzheimer's disease were randomly allocated to four groups: 17 patients received only social support, 18 cognitive training twice a week, in 17 cognitive training was combined with pyritinol 2 x 600 mg/day and in 18 cognitive

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