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Merck
CN

P7171

Pyrithioxin

analytical standard

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About This Item

Empirical Formula (Hill Notation):
C16H20N2O4S2
CAS Number:
Molecular Weight:
368.47
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
214-150-1
MDL number:
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InChI

1S/C16H20N2O4S2/c1-9-15(21)13(5-19)11(3-17-9)7-23-24-8-12-4-18-10(2)16(22)14(12)6-20/h3-4,19-22H,5-8H2,1-2H3

InChI key

SIXLXDIJGIWWFU-UHFFFAOYSA-N

SMILES string

Cc1ncc(CSSCc2cnc(C)c(O)c2CO)c(CO)c1O

grade

analytical standard

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

vitamins, nutraceuticals, and natural products

format

neat

Quality Level

General description

Pyrithioxin is a member of the vitamin B6 class of compounds.

Application

Pyrithioxin may be used as an analytical reference standard for the determination of the analyte in pharmaceutical formulations and biological samples by spectrophotometric and chromatographic techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class

11 - Combustible Solids

wgk

WGK 2


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Determination of Pyrithioxin and Its Metabolites in Blood and Urine of Dogs by High-Performance Liquid Chromatography
KITAO K, et al.
Chemical & Pharmaceutical Bulletin, 25(6), 1335-1342 (1977)
Occupational contact dermatitis due to pyritinol.
W Wigger-Alberti et al.
Contact dermatitis, 37(2), 91-92 (1997-08-01)
Spectrophotometric Determination of Pyrithioxin in Dosage Forms
Belal F, et al.
Analytical Letters, 19(13-14), 1533-1543 (1986)
Spectrophotometric determination of pyrithioxin in pharmaceutical preparations
Hassan SM, et al.
Spectroscopy Letters, 23(10), 1273-1284 (1990)
H Hartmann et al.
Neuropharmacology, 32(2), 119-125 (1993-02-01)
The effect of pyritinol, a commonly used nootropic drug, on receptor properties and function was investigated in different neuronal systems, possibly associated with age-related decline in brain function. Chronic treatment (15 days) of aged (22 months) female NMRI mice with

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