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PHR1130

Supelco

Potassium gluconate

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):
Potassium D-gluconate, D-Gluconic acid potassium salt, 2,3,4,5,6-Pentahydroxycaproic acid potassium salt
Empirical Formula (Hill Notation):
C6H11KO7
CAS Number:
Molecular Weight:
234.25
Beilstein:
3919448
EC Number:
MDL number:
PubChem Substance ID:
E Number:
E577
NACRES:
NA.24

Quality Level

grade

certified reference material
pharmaceutical secondary standard

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

183 °C (dec.) (lit.)

application(s)

cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)

format

neat

pharmacopeia traceability

traceable to USP 1550001

storage temp.

2-30°C

SMILES string

[K+].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O

InChI

1S/C6H12O7.K/c7-1-2(8)3(9)4(10)5(11)6(12)13;/h2-5,7-11H,1H2,(H,12,13);/q;+1/p-1/t2-,3-,4+,5-;/m1./s1

InChI key

HLCFGWHYROZGBI-JJKGCWMISA-M

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General description

Potassium Gluconate is a potassium salt of gluconic acid. It is a commonly administered nutrient supplement form of potassium.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Potassium Gluconate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA7151in the slot below. This is an example certificate only and may not be the lot that you receive.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Potassium Gluconate
USP42-NF37: United States Pharmacopeia and National Formulary
United States Pharmacopeia/National Formulary, 41(6), 3590-3590 (2018)
Herb, nutrient, and drug interactions: clinical implications and therapeutic strategies.
Stargrove MB, et al.
Herb, Nutrient, and Drug Interactions: Clinical Implications and Therapeutic Strategies (2008)
Ubaid H Shah et al.
Clinical nutrition (Edinburgh, Scotland), 32(2), 193-199 (2012-09-18)
Acute lower respiratory infections are the most frequent illnesses globally in children less than 5 years old. The aim of this randomized double blind controlled trial is to assess the effectiveness of zinc gluconate supplementation for 2 months period compared
Michael T Rose et al.
Planta, 236(4), 959-973 (2012-04-25)
Plants are routinely subjected to multiple environmental stresses that constrain growth. Zinc (Zn) deficiency and high bicarbonate are two examples that co-occur in many soils used for rice production. Here, the utility of metabolomics in diagnosing the effect of each
Jeffrey E Nowak et al.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 13(5), e323-e329 (2012-07-05)
We previously demonstrated that altered zinc homeostasis is an important feature of pediatric sepsis, thus raising the possibility of zinc supplementation as a therapeutic strategy in sepsis. Herein, we tested the hypothesis that prophylactic zinc supplementation would be beneficial in

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