Skip to Content
Merck
CN

PHR1326

Calcium carbonate

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

Calcium carbonate

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Linear Formula:
CaCO3
CAS Number:
471-34-1
Molecular Weight:
100.09
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329823311
EC Number:
207-439-9
Beilstein/REAXYS Number:
8008338
MDL number:
MFCD00010906

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Calcium carbonate, Pharmaceutical Secondary Standard; Certified Reference Material

InChI key

VTYYLEPIZMXCLO-UHFFFAOYSA-L

InChI

1S/CH2O3.Ca/c2-1(3)4;/h(H2,2,3,4);/q;+2/p-2

SMILES string

[Ca++].[O-]C([O-])=O

grade

certified reference material
pharmaceutical secondary standard

agency

traceable to USP 1086403

API family

calcium carbonate

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

density

2.93 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

Quality Level

300

Looking for similar products? Visit Product Comparison Guide

Related Categories

Analysis Note

These secondary standards offer multi-traceability to the US and EP primary standards, where they are available.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Calcium carbonate is a material that is widely found in nature, and is commonly referred to as calcite. Calcium carbonate is used in such processes as the manufacture of paper, paints, glass, and ceramics, the compounding of polymers, environmental applications such as wastewater treatment, and as an extender in paints and coatings.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAC3446 in the slot below. This is an example certificate only and may not be the lot that you receive.

wgk

nwg

Storage Class

13 - Non Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Calcium carbonate urolithiasis in an adult male cynomolgus monkey.
C M O'Rourke et al.
Laboratory animal science, 45(2), 222-224 (1995-04-01)
Julyan H E Cartwright et al.
Angewandte Chemie (International ed. in English), 51(48), 11960-11970 (2012-11-06)
Although the polymorphism of calcium carbonate is well known, and its polymorphs--calcite, aragonite, and vaterite--have been highly studied in the context of biomineralization, polyamorphism is a much more recently discovered phenomenon, and the existence of more than one amorphous phase
Dongni Ren et al.
Micron (Oxford, England : 1993), 42(3), 228-245 (2010-10-19)
The review focuses on the effects of several important additives and templates controlling the calcium carbonate crystals formation and the complexity of the crystal morphologies in vitro. Additives include soluble matrices extracted from shells and pearls, amino-acids, magnesium ions and
Polysaccharides and proteoglycans in calcium carbonate-based biomineralization.
José L Arias et al.
Chemical reviews, 108(11), 4475-4482 (2008-07-26)
Ling Li et al.
Nature materials, 13(5), 501-507 (2014-04-01)
Hierarchical composite materials design in biological exoskeletons achieves penetration resistance through a variety of energy-dissipating mechanisms while simultaneously balancing the need for damage localization to avoid compromising the mechanical integrity of the entire structure and to maintain multi-hit capability. Here
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service