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Warfarin Sodium

Pharmaceutical Secondary Standard; Certified Reference Material

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Synonym(s):
3-(α-Acetonylbenzyl)-4-hydroxycoumarin sodium salt, 4-Hydroxy-3-(3-oxo-1-phenylbutyl)coumarin
Linear Formula:
C19H15O4Na
CAS Number:
129-06-6
Molecular Weight:
330.31
EC Number:
204-929-4
MDL number:
MFCD00083223
PubChem Substance ID:
329822599
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Quality Level

300

Agency

traceable to BP 672
traceable to Ph. Eur. W0100000
traceable to USP 1719000

API family

warfarin

CofA

current certificate can be downloaded

packaging

pkg of 1 g

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

[Na].CC(=O)CC(c1ccccc1)C2=C(O)c3ccccc3OC2=O

InChI

1S/C19H16O4.Na/c1-12(20)11-15(13-7-3-2-4-8-13)17-18(21)14-9-5-6-10-16(14)23-19(17)22;/h2-10,15,21H,11H2,1H3;/q;+1/p-1

InChI key

KYITYFHKDODNCQ-UHFFFAOYSA-M

Gene Information

human ... VKORC1(79001)

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General description

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to pharmacopeia primary standards. Warfarin Sodium is an anticoagulant rodenticide, commonly used for the control of rodents such as rats, mice, etc. in surroundings, commercial and industrial sites.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Warfarin Sodium may be used pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using square-wave adsorptive cathodic stripping voltammetry.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA2743 in the slot below. This is an example certificate only and may not be the lot that you receive.

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Statements

H300 - H360 - H412

Hazard Classifications

Acute Tox. 2 Oral - Aquatic Chronic 3 - Repr. 1B

Storage Class Code

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Assay of anti-coagulant drug warfarin sodium in pharmaceutical formulation and human biological fluids by square-wave adsorptive cathodic stripping voltammetry
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