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PHR1482

Supelco

Ferrous Fumarate

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):
Iron(II) fumarate, Ferrous fumarate
Empirical Formula (Hill Notation):
C4H2FeO4
CAS Number:
Molecular Weight:
169.90
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

Quality Level

grade

certified reference material
pharmaceutical secondary standard

CofA

current certificate can be downloaded

packaging

pkg of 1 g

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

O=C1O[Fe]OC(=O)\C=C\1

InChI

1S/C4H4O4.Fe/c5-3(6)1-2-4(7)8;/h1-2H,(H,5,6)(H,7,8);/q;+2/p-2/b2-1+;

InChI key

PMVSDNDAUGGCCE-TYYBGVCCSA-L

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General description

Ferrous fumarate is a commonly used inexpensive substitute for other forms of iron, that is employed as a food iron fortificant.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Ferrous Fumarate may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations by atomic absorption spectrophotometry (AAS).

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA3030 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Ferrous Fumarate
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia/National Formulary, 40(5), 1853-1853 (2015)
Kimberly S Balay et al.
Journal of pediatric gastroenterology and nutrition, 50(5), 545-550 (2010-07-20)
Ferrous fumarate is a common, inexpensive iron form increasingly used instead of ferrous sulfate as a food iron supplement. However, few data exist as to whether juices enhance iron absorption from ferrous fumarate. We studied 21 children, ages 4.0 to

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