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PHR1495

Trientine Hydrochloride

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

Triethylenetetramine dihydrochloride, N,N′-Bis(2-aminoethyl)-1,2-ethanediamine dihydrochloride

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About This Item

Linear Formula:
NH2CH2CH2(NHCH2CH2)2NH2 · 2HCl
CAS Number:
38260-01-4
Molecular Weight:
219.16
UNSPSC Code:
12352200
NACRES:
NA.24
PubChem Substance ID:
329823417
EC Number:
253-854-3
Beilstein/REAXYS Number:
5961763
MDL number:
MFCD00012889

Key Documents

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InChI

1S/C6H18N4.2ClH/c7-1-3-9-5-6-10-4-2-8;;/h9-10H,1-8H2;2*1H

InChI key

WYHIICXRPHEJKI-UHFFFAOYSA-N

SMILES string

Cl.NCCNCCNCCN

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to USP 1683504

API family

trientine hydrochloride

CofA

current certificate can be downloaded

packaging

pkg of 500 mg

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

Quality Level

300

General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Trientine Hydrochloride is administered for relief of symptoms of Wilson′s disease for penicillamine intolerance, hence is employed as an oral medication for the treatment of an inherited defect in copper metabolism.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA3043 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

pictograms

CorrosionExclamation mark
GHS05,GHS07

signalword

Danger

Hazard Classifications

Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1A

Storage Class

8A - Combustible corrosive hazardous materials

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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