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PHR1615

Supelco

Ritodrine Hydrochloride

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):
1-(4-Hydroxyphenyl)-2-[2-(4-hydroxyphenyl)ethylamino]propanol, N-(p-Hydroxyphenethyl)-4-hydroxynorephedrine hydrochloride, Ritodrine hydrochloride
Empirical Formula (Hill Notation):
C17H21NO3 · HCl
CAS Number:
Molecular Weight:
323.81
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.24

Quality Level

grade

certified reference material
pharmaceutical secondary standard

CofA

current certificate can be downloaded

packaging

pkg of 1 g

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

pharmacopeia traceability

traceable to PhEur 586
traceable to USP 1604701

storage temp.

2-8°C

SMILES string

Cl.C[C@H](NCCc1ccc(O)cc1)[C@H](O)c2ccc(O)cc2

InChI

1S/C17H21NO3.ClH/c1-12(17(21)14-4-8-16(20)9-5-14)18-11-10-13-2-6-15(19)7-3-13;/h2-9,12,17-21H,10-11H2,1H3;1H/t12-,17-;/m0./s1

InChI key

IDLSITKDRVDKRV-XHXSRVRCSA-N

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General description

Ritodrine Hydrochloride is a potent tocolytic drug and a selective γ2-adrenoceptor agonist, widely used for the control of premature labor.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Ritodrine Hydrochloride may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using spectrophotometric technique.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC3901 in the slot below. This is an example certificate only and may not be the lot that you receive.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Spectrophotometric method for the determination of ritodrine hydrochloride and amoxicillin
Revanadiddappa DH, et al.
Analytical Sciences, 15(7), 661-664 (1999)
Novel method for the spectrophotometric determination of isoniazid and ritodrine hydrochloride
Nagaraja P, et al.
Turkish Journal of Chemistry, 26(5), 743-750 (2002)

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