Key Documents

View All Documentation

PHR1760

Nevirapine Related Compound A

Name: Nevirapine Related Compound A
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

11-Ethyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2′,3′-e][1,4]diazepin-6-one, 5,11-DIHYDRO-6H-11-ETHYL- 4-METHYL-DIPYRIDO[3,2-b:2’,3’- e][1,4]DIAZEPIN-6-ONE

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):

C₁₄H₁₄N₄O

CAS Number:

133627-17-5

Molecular Weight:

254.29

UNSPSC Code:

41116107

NACRES:

NA.24

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Quality Level

300

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to USP 1460725

API family

nevirapine

CofA

current certificate can be downloaded

packaging

pkg of 50 mg

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

InChI

1S/C14H14N4O/c1-3-18-12-10(5-4-7-15-12)14(19)17-11-9(2)6-8-16-13(11)18/h4-8H,3H2,1-2H3,(H,17,19)

InChI key

HDVZWQWXAQRFKJ-UHFFFAOYSA-N

Description

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Nevirapine Related Compound A is an impurity of nevirapine. Nevirapine is a non-nucleoside reverse transcriptase inhibitor (NNRTI), which belongs to the class of antiretroviral drugs. It acts by inhibiting the reverse transcriptase enzyme, thus stopping the multiplication of HIV. It is highly effective against advanced HIV disease.

Application

Nevirapine may be used as a pharmaceutical reference standard for the analysis of the analyte in pharmaceutical formulations and fixed dose combinations by chromatography.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAA8553 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Still not finding the right product?

Explore all of our products under Nevirapine Related Compound A

pictograms

GHS06,GHS08

signalword

Danger

hcodes

H301,H317,H373

pcodes

P280 - P301 + P310 + P330 - P302 + P352 - P314

Hazard Classifications

Acute Tox. 3 Oral - Skin Sens. 1 - STOT RE 2 Inhalation

target_organs

Liver

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

MEKC determination of antiretroviral reverse transcriptase inhibitors lamivudine, stavudine, and nevirapine in pharmaceutical formulations

Sekar R and Azhaguvel S

Chromatographia, 67(5-6), 389-398 (2008)

Nevirapine

USP42-NF37

United States Pharmacopeia/National Formulary, 32(3), 3101-3101 (2018)

Simultaneous determination of lamivudine, stavudine and nevirapine in antiretroviral fixed dose combinations by high performance liquid chromatography

Kapoor N, et al.

Analytica Chimica Acta, 570(1), 41-45 (2006)

View All Related Papers

Global Trade Item Number

SKU	GTIN
PHR1760-50MG	04061835079971