Skip to Content
Merck
CN

PHR1773

Ranitidine Related Compound A

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

2-{{{5-[(Dimethylamino)methyl]furan-2-yl}methyl}sulfanyl}ethanamine hemifumarate salt, 2-{{{5-[(DIMETHYLAMINO)METHYL] FURAN-2-YL}METHYL}SULFANYL} ETHANEAMINEHEMIFUMARATE SALT, Ranitidine Impurity B, 2-{{{5-[(Dimethylamino)methyl]-2-furanyl}methyl}thio}ethylamine hemifumarate salt, 5-{[(2-Aminoethyl)thio]methyl}-N,N-dimethyl- 2-furanmethanamine hemifumarate salt, Ranitidine diamine hemifumarate salt

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C10H18N2OS · 0.5 C4H4O4
CAS Number:
91224-69-0
Molecular Weight:
272.36
UNSPSC Code:
41116107
NACRES:
NA.24

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

InChI

1S/C10H18N2OS.C4H4O4/c1-12(2)7-9-3-4-10(13-9)8-14-6-5-11;5-3(6)1-2-4(7)8/h3-4H,5-8,11H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1+

InChI key

VKUKMWIQZWDCGK-WLHGVMLRSA-N

SMILES string

OC(=O)\C=C\C(O)=O.CN(C)Cc1ccc(CSCCN)o1

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to USP 1598507

API family

ranitidine

CofA

current certificate can be downloaded

packaging

pkg of 100 mg

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

Quality Level

300

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Ranitidine Related Compound A is an impurity of ranitidine, an inhibitor of gastric acid secretion. Ranitidine is widely used for treating gastric and duodenal ulcers.

Application

Ranitidine may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using kinetic spectrophotometric technique and electrochemical method.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAC0714 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Simultaneous determination of ranitidine and metronidazole in pharmaceutical formulations at poly (chromotrope 2B) modified activated glassy carbon electrodes
Li X and Xu G
Journal of food and drug analysis, 22(3), 345-349 (2014)
Kinetic spectrophotometric determination of nizatidine and ranitidine in pharmaceutical preparations
Hassan ME and Belal F
Journal of Pharmaceutical and Biomedical Analysis, 27(1-2), 31-38 (2002)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service