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PHR1929

Supelco

Ubidecarenone

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):
Ubiquinone-10, Ubiquinone 50, Q-10, Coenzyme Q10
Empirical Formula (Hill Notation):
C59H90O4
CAS Number:
Molecular Weight:
863.34
Beilstein:
1900141
EC Number:
MDL number:
NACRES:
NA.24

Quality Level

grade

certified reference material
pharmaceutical secondary standard

CofA

current certificate can be downloaded

packaging

pkg of 500 mg

application(s)

pharmaceutical

format

neat

pharmacopeia traceability

traceable to PhEur U0020000
traceable to USP 1705301

storage temp.

-10 to -25°C

SMILES string

O=C(C(OC)=C1OC)C(C/C=C(C)/CC/C=C(CC/C=C(CC/C=C(CC/C=C(CC/C=C(CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CCC=C(C)C)\C)\C)\C)\C)\C)=C(C)C1=O

InChI

1S/C59H90O4/c1-44(2)24-15-25-45(3)26-16-27-46(4)28-17-29-47(5)30-18-31-48(6)32-19-33-49(7)34-20-35-50(8)36-21-37-51(9)38-22-39-52(10)40-23-41-53(11)42-43-55-54(12)56(60)58(62-13)59(63-14)57(55)61/h24,26,28,30,32,34,36,38,40,42H,15-23,25,27,29,31,33,35,37,39,41,43H2,1-14H3/b45-26+,46-28+,47-30+,48-32+,49-34+,50-36+,51-38+,52-40+,53-42+

InChI key

ACTIUHUUMQJHFO-UPTCCGCDSA-N

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General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Ubidecarenone is a dietary supplement, and a cardiovascular agent employed in the treatment of angina pectoris and congestive cardiac failure. Its mode of action involves the improvement of cardiac output by increasing the contractive force of the heart through positive inotropic action.

Application

Ubidecarenone may be used as a pharmaceutical reference standard for the quantification of the analyte in combined pharmaceutical dosage form using reversed-phase high-performance liquid chromatography technique.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAB0979 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Method development and validation for the simultaneous estimation of lycopene and ubidecarenone by RP-HPLC in combined pharmaceutical dosage form
SVS, et al.
Journal of Drug Delivery and Therapeutics, 6(5), 46-51 (2016)

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