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Merck
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Q5001

Quinidine gluconate salt

analytical standard

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About This Item

Empirical Formula (Hill Notation):
C20H24N2O2 · C6H12O7
CAS Number:
7054-25-3
Molecular Weight:
520.57
NACRES:
NA.24
PubChem Substance ID:
329823867
UNSPSC Code:
41116107
EC Number:
230-333-9
MDL number:
MFCD00067566

Key Documents

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InChI key

XHKUDCCTVQUHJQ-LCYSNFERSA-N

InChI

1S/C20H24N2O2.C6H12O7/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;7-1-2(8)3(9)4(10)5(11)6(12)13/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;2-5,7-11H,1H2,(H,12,13)/t13-,14-,19+,20-;2-,3-,4+,5-/m01/s1

SMILES string

OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.[H][C@@]12CCN(C[C@@H]1C=C)[C@]([H])(C2)[C@@H](O)c3ccnc4ccc(OC)cc34

grade

analytical standard

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

impurities

≤20% Dihydroquinidine (according to USP specifications., actual content given on label)

application(s)

food and beverages

format

neat

Quality Level

100

Gene Information

human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Class IA antiarrhythmic; potassium channel blocker.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

涉药品监管产品
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The treatment of malaria.
C L Bailey
The New England journal of medicine, 336(10), 733-733 (1997-03-06)
C I Berul et al.
Circulation, 94(10), 2641-2648 (1996-11-15)
This report describes a novel in vivo mouse epicardial cardiac electrophysiology study based on clinical protocols used to evaluate cardiac conduction in human patients. The technique allows extensive electrophysiological evaluation, including the response to pacing, programmed stimulation, and pharmacological agents.
MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports, 40(RR-4), 21-23 (1991-04-19)
CDC has recently reviewed data on the reported incidence in the United States of Plasmodium falciparum malaria and has evaluated available information on the effective management of severe life-threatening infections. As a result of this review, CDC has concluded that
Availability of parenteral quinidine gluconate for treatment of severe or complicated malaria.
MMWR. Morbidity and mortality weekly report, 45(23), 494-495 (1996-06-14)
Malaria and hereditary elliptocytosis.
Fouad N Boctor et al.
American journal of hematology, 83(9), 753-753 (2007-08-19)
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