R8881
Rhodamine B isothiocyanate–Dextran
Powder
Synonym(s):
RITC-Dextran
Product Name
Rhodamine B isothiocyanate–Dextran, average mol wt ~10,000
form
powder
Quality Level
mol wt
average mol wt ~10,000
extent of labeling
0.002-0.01 mol RITC per mol glucose
technique(s)
titration: suitable
color
light pink to red
very dark purple
solubility
water: 10 mg/mL, clear, pink
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
2-8°C
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General description
Rhodamine B is a thiol-reactive and photostable fluorescent dye. Rhodamine B isothiocyanate is an aminoxanthene that possesses carboxylic acid and isothiocyanate substituents on the pendant phenyl ring.
Application
Dextran labeled with rhodamine B isothiocyanate for possible use in perfusion studies in animals.
Rhodamine B isothiocyanate (NE)-labeled dextran is often used as a fluorescent probe for studies of endocytotic activity and to detect the migrated of marked cells. It is also suitable for perfusion studies in animals. Rhodamine B isothiocyanate–Dextran has been used for in vivo zebrafish blood-brain barrier (BBB) dye diffusion assay.
Biochem/physiol Actions
Rhodamine B stains the tissue in red-violet color and emits a bright red color when fluoresced. It is highly preferred for marking insects.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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