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Merck
CN

S7507

Sulfamethoxazole

Synonym(s):

4-Amino-N-(5-methyl-3-isoxazolyl)benzenesulfonamide, N1-(5-Methylisoxazol-3-yl)sulfanilamide

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About This Item

Empirical Formula (Hill Notation):
C10H11N3O3S
CAS Number:
Molecular Weight:
253.28
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
211-963-3
Beilstein/REAXYS Number:
6732984
MDL number:
Technical Service
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Quality Level

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

storage temp.

2-8°C

SMILES string

Cc1cc(NS(=O)(=O)c2ccc(N)cc2)no1

InChI

1S/C10H11N3O3S/c1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h2-6H,11H2,1H3,(H,12,13)

InChI key

JLKIGFTWXXRPMT-UHFFFAOYSA-N

General description

Sulfamethoxazole is a bacteriostatic antibiotic, belonging to the class of sulfonamides. It is widely used in the treatment of pneumocystis, coccidiosis, gastroenteritis, diarrhea, respiratory diseases such as pneumonia, etc.

Application

Sulfamethoxazole is used as an analytical reference standard for the quantification of the analyte in milk samples using analytical and microbiological assay technique.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase.
Mode of Action: Inhibits folic acid synthesis in prokaryotes.
Anti-microbial Spectrum: Gram positive, Gram negative, Chlamydia
Mode of Resistance: Alteration of dihydropteroate synthase or alternative pathway for folic acid synthesis.


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pictograms

Health hazardEnvironment

signalword

Warning

Hazard Classifications

Aquatic Chronic 2 - Repr. 2

Storage Class

11 - Combustible Solids

wgk

WGK 2

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves



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Related Content

Product Information Sheet


Drugs: Synonyms and Properties (2017)
Use of chemometric techniques to design a microbiological method for sulfonamide detection in milk
Nagel.GO, et al.
Czech Journal of Food Sciences, 31(6), 627-632 (2013)
Sulfamethoxazole abatement by means of ozonation
Journal of Hazardous Materials, 150(3), 790-794 (2008)



Global Trade Item Number

SKUGTIN
S7507-100G04061836960018
S7507-10G04061835564569