SMB00971
4-Ethylphenol sodium sulfate
Synonym(s):
4-Ethylphenyl sulfate sodium salt
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About This Item
Empirical Formula (Hill Notation):
C8H9NaO4S
Molecular Weight:
224.21
NACRES:
NA.77
UNSPSC Code:
51171629
Assay:
≥98.0% (HPLC)
Form:
solid
General description
4-Ethylphenol sodium sulfate is the sodium salt of 4-Ethylphenyl sulfate (4EPS). 4-Ethylphenyl sulfate is a gut microbial metabolite derived from tyrosine, which is converted into 4-ethylphenol and subsequently sulfated in the liver. Upregulated urine 4EPS levels are found among rats prone to insulin resistance and obesity. Increased plasma 4EPS was reported in a murine model of autism, and mice treated with 4EPS displayed anxiety-like behaviours. Higher levels of 4-ethylphenylsulfate were also found in plasma, liver, heart and kidneys in a rat model of chronic kidney disease. 4EPS is a component of the urine of male rats, and both 4-ethylphenyl sulfate and 4-ethylphenol are thought to participate in pheromonal communication. p-Cresol-sulfate and 4-ethylphenyl sulfate are thought to derive from tyrosine and have similar bioactivities, however their enzymatic production may differ.
Application
Metabolomics research
Microbiome research
Microbiome research
Other Notes
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Lauren J Rajakovich et al.
Natural product reports, 36(4), 593-625 (2018-11-20)
Covering: up to the end of 2017 The human body is composed of an equal number of human and microbial cells. While the microbial community inhabiting the human gastrointestinal tract plays an essential role in host health, these organisms have
Houkai Li et al.
Journal of proteome research, 6(4), 1364-1370 (2007-02-22)
In conventional pharmacological studies, intersubject differences within an animal strain are normally neglected, leading to variations in pharmacological outcomes in response to the same stimulus. Using two classical experimental models, the Streptozotocin (STZ)-induced diabetic model of Wistar rats and the
S Achiraman et al.
Journal of biosciences, 27(7), 679-686 (2003-02-07)
The present study was carried out to investigate the chemical nature of the urine of male mice and to assess its bioactivity. Urine of mature male mice was extracted with dichloromethane (1 : 1 ratio v/v) and analysed by gas-chromatography
Global Trade Item Number
| SKU | GTIN |
|---|---|
| SMB00971-50MG | 04065265044042 |
| SMB00971-250MG | 04065265044035 |