SMB01335
AFMK
≥95% (HPLC)
别名:
AFMK, AFMKA, NSC-688263, NSC688263, N-[3-[2-(Formylamino)-5-methoxyphenyl]-3-oxopropyl]acetamide, NSC 688263
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关于此项目
经验公式（希尔记法）:
C13H16N2O4
化学文摘社编号:
分子量:
264.28
UNSPSC Code:
12352116
NACRES:
NA.77
MDL number:
Quality Segment
assay
≥95% (HPLC)
form
solid
storage temp.
2-8°C
SMILES string
COc1ccc(NC=O)c(c1)C(=O)CCNC(C)=O
InChI
1S/C13H16N2O4/c1-9(17)14-6-5-13(18)11-7-10(19-2)3-4-12(11)15-8-16/h3-4,7-8H,5-6H2,1-2H3,(H,14,17)(H,15,16)
InChI key
JYWNYMJKURVPFH-UHFFFAOYSA-N
General description
Melatonin and its metabolites are being studied for their antioxidant properties and their protective effects against oxidative stress in both mammals and in plants. N1-Acetyl-5-methoxykynuramine (AMK) and its direct precursor N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK) are two metabolites that contribute to the antioxidant properties of melatonin.
Application
Metabolomics research
Biochem/physiol Actions
AFMK is a melatonin metabolite first detected in rat brain; demonstrates antioxidant and free radical scavenging activities in several experimental models; inhibits LPS-mediated production of TNFα and IL-8 in neutrophils; useful tool in the study of melatonin metabolism.
AFMK is a melatonin oxidation product.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable