SMB01368
Octahydrocurcumin
≥95% (HPLC)
Synonym(s):
Hexahydrobisdemethoxycurcumin, Hexahydrocurcuminol, OHC
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About This Item
Empirical Formula (Hill Notation):
C21H28O6
CAS Number:
Molecular Weight:
376.44
MDL number:
UNSPSC Code:
12352205
NACRES:
NA.21
biological source
synthetic
Quality Level
Assay
≥95% (HPLC)
form
solid
storage temp.
2-8°C
SMILES string
O[C@H](C[C@@H](O)CCc2cc(c(cc2)O)OC)CCc1cc(c(cc1)O)OC
InChI
1S/C21H28O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h5-6,9-12,16-17,22-25H,3-4,7-8,13H2,1-2H3/t16-,17-/m0/s1
InChI key
OELMAFBLFOKZJD-IRXDYDNUSA-N
General description
Octahydrocurcumin (OHC) is an active metabolite of curcumin. OHC has shown anti-inflammatory activity and antioxidant effects on LPS-stimulated inflammation through inhibition of the NF-κB signaling pathway.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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Zhen-Biao Zhang et al.
Frontiers in pharmacology, 9, 1181-1181 (2018-11-06)
Curcumin (CUR), a promising naturally occurring dietary compound, is commonly recognized as the potential anti-inflammatory agent. While the application of CUR was hampered by its low stability and poor systemic bioavailability, it has been suggested that the biological activities of
Qing-Feng Xie et al.
Evidence-based complementary and alternative medicine : eCAM, 2020, 8856135-8856135 (2021-01-12)
Curcumin (CUR) possesses pronounced anti-inflammatory and antioxidant activities. Generally, the clinical application of CUR is restricted due to its apparent unstability and poor absorption, and the biological activities of CUR may be closely associated with its metabolites. Tetrahydrocurcumin (THC) and
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