Skip to Content
Merck
CN

SMB01382

2-Methoxyestrone

≥95% (HPLC), from synthetic, solid

Synonym(s):

2,3-Dihydroxy-1,3,5(10)-estratrien-17-one 2-methyl ether, 2-Hydroxyestrone 2-methyl ether, 3-Hydroxy-2-methoxy-1,3,5(10)-estratrien-17-one

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C19H24O3
CAS Number:
362-08-3
Molecular Weight:
300.39
UNSPSC Code:
12352211
NACRES:
NA.79
MDL number:
MFCD00056413

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

InChI

1S/C19H24O3/c1-19-8-7-12-13(15(19)5-6-18(19)21)4-3-11-9-16(20)17(22-2)10-14(11)12/h9-10,12-13,15,20H,3-8H2,1-2H3/t12-,13+,15-,19-/m0/s1

InChI key

WHEUWNKSCXYKBU-QPWUGHHJSA-N

SMILES string

C[C@@]12[C@](CCC2=O)([H])[C@]3([H])CCC4=CC(O)=C(OC)C=C4[C@@]3([H])CC1

biological source

synthetic

assay

≥95% (HPLC)

form

solid

mp

187-190 °C

storage temp.

2-8°C

Quality Level

200

Related Categories

General description

2-Methoxyestrone is an endogenous, naturally occurring methoxylated catechol estrogen and an estrone metabolite formed by catechol O-methyltransferase via the intermediate 2-hydroxyestrone. Unlike estrone but similarly to 2-hydroxyestrone and 2-methoxyestradiol, 2-methoxyestrone has very low affinity for the estrogen receptor and lacks significant estrogenic activity

Preparation Note

Heat sensitive

pictograms

Health hazardEnvironment
GHS08,GHS09

signalword

Warning

hcodes

H351,H410

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

涉药品监管产品
This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000317466
0000317466
0000237988
0000237987
0000224632

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Urinary estrogen metabolites and gastric cancer risk among postmenopausal women.
Camargo MC, et al.
Cancer reports (Hoboken, N.J.), 5, e1574-e1574 (2022)
Reproducibility of fifteen urinary estrogens and estrogen metabolites over a 2- to 3-year period in premenopausal women.
Eliassen AH, et al.
Cancer Epidemiology, Biomarkers & Prevention, 18, 2860-2868 (2009)
Individual and cyclic estrogenic profile in women: Structure and variability of the data.
Bozzolino C, et al.
Steroids, 150, 108432-108432 (2019)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service