T0274
Trifluoroacetic acid
liquid
Synonym(s):
TFA
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About This Item
Linear Formula:
CF3COOH
CAS Number:
Molecular Weight:
114.02
EC Number:
200-929-3
UNSPSC Code:
12352200
MDL number:
Beilstein/REAXYS Number:
742035
vapor density
3.9 (vs air)
vapor pressure
97.5 mmHg ( 20 °C)
form
liquid
refractive index
n20/D 1.3 (lit.)
bp
72.4 °C (lit.)
mp
−15.4 °C (lit.)
density
1.489 g/mL at 20 °C (lit.), 1.49 g/mL at 25 °C (lit.)
SMILES string
OC(C(F)(F)F)=O
InChI
1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7)
InChI key
DTQVDTLACAAQTR-UHFFFAOYSA-N
Application
Suitable for gas phase protein sequencing.
Preparation Note
Distilled from chromium(VI) oxide under nitrogen, treated with aluminum oxide, then redistilled from dithiothreitol under nitrogen.
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Danger
hcodes
Hazard Classifications
Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1A
Storage Class
8A - Combustible corrosive hazardous materials
wgk
WGK 2
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Regulatory Information
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Mangesh R Bhide et al.
BMC research notes, 2, 134-134 (2009-07-17)
Borreliae employ multiple immune evasive strategies such as binding to complement regulatory proteins [factor H (fH) and factor H like-1 (FHL1)], differential regulation of surface membrane proteins, antigenic variation, and binding of plasminogen/plasmin and matrix metalloproteinases. As a complement regulatory
Miklos Guttman et al.
Proteomics, 9(22), 5016-5028 (2009-09-23)
The low density lipoprotein receptor-related protein 1 (LRP1) mediates internalization of a large number of proteins and protein-lipid complexes and is widely implicated in Alzheimer's disease. The cytoplasmic domain of LRP1 (LRP1-CT) can be phosphorylated by activated protein-tyrosine kinases at
Younggyu Kim et al.
Nucleic acids research, 36(19), 6143-6154 (2008-10-01)
We have developed an approach that enables nonradioactive, ultrasensitive (attamole sensitivity) site-specific protein-protein photocrosslinking, and we have applied the approach to the analysis of interactions of alpha-helix 2 (H2) of human TATA-element binding protein (TBP) with general transcription factor TFIIA