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Merck
CN

T8258

Trifluoroacetic anhydride

liquid

Synonym(s):

TFAA

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About This Item

Linear Formula:
(CF3CO)2O
CAS Number:
407-25-0
Molecular Weight:
210.03
EC Number:
206-982-9
UNSPSC Code:
12352100
MDL number:
MFCD00000416
Beilstein/REAXYS Number:
746197

Key Documents

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vapor pressure

6.28 psi ( 20 °C)

form

liquid

color

clear colorless

refractive index

n20/D 1.3 (lit.)

bp

39.5-40 °C (lit.)

mp

−65 °C (lit.)

density

1.511 g/mL at 20 °C (lit.)

SMILES string

FC(F)(F)C(=O)OC(=O)C(F)(F)F

InChI

1S/C4F6O3/c5-3(6,7)1(11)13-2(12)4(8,9)10

InChI key

QAEDZJGFFMLHHQ-UHFFFAOYSA-N

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pictograms

CorrosionExclamation mark
GHS05,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1A

supp_hazards

EUH014

Storage Class

8A - Combustible corrosive hazardous materials

wgk

WGK 2

ppe

Faceshields, Gloves, Goggles

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
108K0158
018K3531
127K3739
107K3721
087K3417

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Angelos Halaris et al.
Journal of psychiatric research, 66-67, 118-126 (2015-05-27)
A pro-inflammatory state and a dysregulation in the tryptophan/kynurenine pathway have been documented in depression. This study examined whether treatment with the SSRI, escitalopram (ESC), could suppress inflammation and favorably shift metabolites of the kynurenine pathway in patients with major
Bjorn J A Berendsen et al.
Analytica chimica acta, 585(1), 126-133 (2007-03-28)
Derivatisation of the avermectines ivermectin (IVM), doramectin (DOR), abamectin (ABA) and eprinomectin (EPR), and the milbemycin moxidectin (MOX) to fluorescent derivatives is commonly used for quantitative analysis at relevant levels using high performance liquid chromatography (HPLC) with fluorescence detection. Problems
L Giannetti et al.
Analytica chimica acta, 700(1-2), 11-15 (2011-07-12)
Avermectines are antiparasitic agents widely used as veterinary drugs for food producing animals. The European Community, due to their side effects, limited the use of these molecules establishing maximum residue limits (MRLs) in some foods. A validated qualitative and quantitative
Sooyeun Lee et al.
Forensic science international, 178(2-3), 207-212 (2008-05-27)
Quality assurance is one of the major issues in forensic analytical laboratories, where the need for a reference material (RM) has rapidly increased. RMs are very useful for method development and validation, internal quality control or proficiency tests. In the
H Christine Lo et al.
Journal of the American Chemical Society, 129(5), 1246-1253 (2007-02-01)
Re(2)O(7), which is known primarily as a strong oxidant, was found to be a highly selective Lewis acid catalyst that affects the heteroacylative dimerization of THF at room temperature. This multicomponent reaction, which involves THF, trifluoroacetic anhydride (TFAA), and a
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