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Y0000245

Ketobemidone impurity C

European Pharmacopoeia (EP) Reference Standard

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Synonym(s):
1-[4-(3-Hydroxyphenyl)piperidin-4-yl]propan-1-one
Empirical Formula (Hill Notation):
C14H19NO2
CAS Number:
15847-72-0
Molecular Weight:
233.31
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

ketobemidone

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

InChI

1S/C14H19NO2/c1-2-13(17)14(6-8-15-9-7-14)11-4-3-5-12(16)10-11/h3-5,10,15-16H,2,6-9H2,1H3

InChI key

BJTDPLRIKDSWIS-UHFFFAOYSA-N

Related Categories

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Ketobemidone impurity C EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

related product

Product No.
Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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U Bondesson et al.
Biomedical mass spectrometry, 10(4), 283-286 (1983-04-01)
An analytical procedure has been developed for the simultaneous determination of ketobemidone and its N-demethylated metabolite, norketobemidone. After isolation from plasma and re-extraction to acidic aqueous phase, the two aminophenols were extracted as ions pairs with tetrabutylammonium to dichloromethane, where
Alvaro J Santos-Neto et al.
Journal of chromatography. A, 1189(1-2), 514-522 (2008-03-22)
Direct analysis, with minimal sample pretreatment, of antidepressant drugs, fluoxetine, imipramine, desipramine, amitriptyline, and nortriptyline in biofluids was developed with a total run time of 8 min. The setup consists of two HPLC pumps, injection valve, capillary RAM-ADS-C18 pre-column and
The mu1 and mu2 opioid receptor binding of ketobemidone, norketobemidone and 3-dimethylamino-1,1-diphenylbutene.
K Kristensen et al.
Pharmacology & toxicology, 79(2), 103-104 (1996-08-01)
U Yasar et al.
Xenobiotica; the fate of foreign compounds in biological systems, 35(8), 785-796 (2005-11-10)
The role of the major drug-metabolizing cytochrome P450 (CYP) enzymes as well as P-glycoprotein (PGP) was investigated in the disposition of ketobemidone in vitro. Formation of norketobemidone from ketobemidone was studied and compared with the activities of 11 major CYP

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