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Y0000397

Lysine acetate

European Pharmacopoeia (EP) Reference Standard

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Synonym(s):
L-Lysine acetate salt, (S)-2,6-Diaminohexanoic acid
Empirical Formula (Hill Notation):
C6H14N2O2 · C2H4O2
CAS Number:
57282-49-2
Molecular Weight:
206.24
MDL number:
MFCD00039069
PubChem Substance ID:
329830932
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

lysine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CC(O)=O.NCCCC[C@H](N)C(O)=O

InChI

1S/C6H14N2O2.C2H4O2/c7-4-2-1-3-5(8)6(9)10;1-2(3)4/h5H,1-4,7-8H2,(H,9,10);1H3,(H,3,4)/t5-;/m0./s1

InChI key

RRNJROHIFSLGRA-JEDNCBNOSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Lysine acetate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Christopher E Berndsen et al.
Nature structural & molecular biology, 21(4), 301-307 (2014-04-05)
E3 ligases carry out the final step in the ubiquitination cascade, catalyzing transfer of ubiquitin from an E2 enzyme to form a covalent bond with a substrate lysine. Three distinct classes of E3 ligases have been identified that stimulate transfer
Thomas Kusch et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(13), 4850-4855 (2014-03-19)
Histone H3 lysine 4 trimethylation (H3K4me3) and the acetylated H2A variant, H2A.Z/v (H2Avac), are enriched at promoters of highly transcribed loci including the stress response genes. Using the inducible Drosophila hsp70 loci as a model, we study here the roles
Francesca Mattiroli et al.
Nature structural & molecular biology, 21(4), 308-316 (2014-04-05)
Ubiquitin and ubiquitin-like modifications are central to virtually all cellular signaling pathways. They occur primarily on lysine residues of target proteins and stimulate a large number of downstream signals. The diversity of these signals depends on the type, location and
Keisuke Miyagawa et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(16), 5950-5955 (2014-04-09)
Telomeres protect DNA ends of linear eukaryotic chromosomes from degradation and fusion, and ensure complete replication of the terminal DNA through recruitment of telomerase. The regulation of telomerase is a critical area of telomere research and includes cis regulation by
Audrey Letourneau et al.
Nature, 508(7496), 345-350 (2014-04-18)
Trisomy 21 is the most frequent genetic cause of cognitive impairment. To assess the perturbations of gene expression in trisomy 21, and to eliminate the noise of genomic variability, we studied the transcriptome of fetal fibroblasts from a pair of
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