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Merck
CN

Y0000658

Iotrolan for system suitability

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Iotrolan

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About This Item

Empirical Formula (Hill Notation):
C37H48I6N6O18
CAS Number:
79770-24-4
Molecular Weight:
1626.23
UNSPSC Code:
41116107
NACRES:
NA.24

Key Documents

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Product Name

Iotrolan for system suitability, European Pharmacopoeia (EP) Reference Standard

SMILES string

Ic1c(c(c(c(c1C(=O)NC(C(O)CO)CO)I)C(=O)NC(C(O)CO)CO)I)N(C)C(=O)CC(=O)N(C)c2c(c(c(c(c2I)C(=O)NC(C(O)CO)CO)I)C(=O)NC(C(O)CO)CO)I

InChI

1S/C37H48I6N6O18/c1-48(32-28(40)22(34(64)44-12(4-50)16(58)8-54)26(38)23(29(32)41)35(65)45-13(5-51)17(59)9-55)20(62)3-21(63)49(2)33-30(42)24(36(66)46-14(6-52)18(60)10-56)27(39)25(31(33)43)37(67)47-15(7-53)19(61)11-57/h12-19,50-61H,3-11H2,1-2H3,(H,44,64)(H,45,65)(H,46,66)(H,47,67)

InChI key

XUHXFSYUBXNTHU-UHFFFAOYSA-N

grade

pharmaceutical primary standard

API family

iotrolan

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

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Application

Iotrolan for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

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Jolanda J de Poorter et al.
The journal of gene medicine, 7(11), 1421-1428 (2005-06-25)
Loosening is a major complication in prosthesis surgery. To stabilize loosened orthopedic implants, the interface tissue surrounding the implant must be removed. As an alternative to manual removal, we explored the possibility of removing the tissue by gene-directed enzyme prodrug
Ingrid Böhm et al.
European journal of radiology, 55(3), 431-436 (2005-09-01)
To test whether mono- or dimeric X-ray contrast media (CM) may induce the de novo production of cysteinyl-leukotriens (cys-LT), that could contribute to allergic/allergy-like side effects. Leukocytes from 39 patients receiving iopromide or iotrolan for routine CT-examination were analyzed for
Marc C Heinrich et al.
Radiology, 235(3), 843-849 (2005-04-23)
To compare the cytotoxic effects of dimeric and monomeric iodinated contrast media on renal tubular cells in vitro with regard to osmolality. LLC-PK1 cells were incubated with ioxithalamate, ioversol, iomeprol-300, iomeprol-150, iodixanol, iotrolan, and hyperosmolar mannitol solutions for 1-24 hours
Marc Heinrich et al.
Investigative radiology, 39(7), 406-412 (2004-06-15)
To investigate whether the lower incidence of vasodilatation upon vascular injection of iotrolan, as compared with monomeric contrast media, is solely the result of its isotonicity. In an organ bath, isolated segments of swine renal arteries, uncontracted or precontracted by
K-F Kreitner et al.
European radiology, 13(2), 320-329 (2003-02-25)
In the age of cost containment and urgent reductions in health care expenditures, new options have to be explored to satisfy both diagnostic requirements and economic limitations. The introduction of low-field MR systems for assessment of joint disorders seemed to
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