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About This Item
Empirical Formula (Hill Notation):
C4H3F7O
CAS Number:
Molecular Weight:
200.05
UNSPSC Code:
41116107
NACRES:
NA.24
Product Name
Sevoflurane, European Pharmacopoeia (EP) Reference Standard
SMILES string
FC(F)(F)C(OCF)C(F)(F)F
InChI
1S/C4H3F7O/c5-1-12-2(3(6,7)8)4(9,10)11/h2H,1H2
InChI key
DFEYYRMXOJXZRJ-UHFFFAOYSA-N
grade
pharmaceutical primary standard
API family
sevoflurane
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
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Application
Sevoflurane EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Other Notes
Sales restrictions may apply.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Inge K Herrmann et al.
Anesthesiology, 119(4), 901-906 (2013-07-23)
Sepsis remains a leading cause of death in intensive care units. There is growing evidence that volatile anesthetics have beneficial immunomodulatory effects on complex inflammation-mediated conditions. The authors investigated the effect of volatile anesthetics on the overall survival of mice
Bjorn Heyse et al.
Anesthesiology, 120(6), 1390-1399 (2014-02-26)
The authors studied the interaction between sevoflurane and remifentanil on bispectral index (BIS), state entropy (SE), response entropy (RE), Composite Variability Index, and Surgical Pleth Index, by using a response surface methodology. The authors also studied the influence of stimulation
Giovanni Landoni et al.
Journal of cardiothoracic and vascular anesthesia, 21(4), 502-511 (2007-08-07)
The authors performed a meta-analysis to investigate whether the cardioprotective effects of volatile anesthetics translate into decreased morbidity and mortality in patients undergoing cardiac surgery. It is commonly believed that the choice of the primary anesthetic agent does not result
Maj-Lis Lindholm et al.
Anesthesia and analgesia, 118(4), 782-787 (2014-03-22)
Preclinical data indicate that anesthesia and surgery may promote cancer growth. We previously found no increased risk of malignant disease within 5 years regarding duration of general anesthesia (TANESTH) and time with Bispectral Index (BIS) under 45 (TBIS < 45)
Jan Kehler et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 55(9), 1513-1518 (2014-07-06)
Phosphodiesterase 10A (PDE10A) plays a key role in the regulation of brain striatal signaling, and several pharmaceutical companies currently investigate PDE10A inhibitors in clinical trials for various central nervous system diseases. A PDE10A PET ligand may provide evidence that a
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