15440
N,N-Dimethylformamide
≥99% (GC)
Synonym(s):
DMF, NSC 5356
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About This Item
Linear Formula:
HCON(CH3)2
CAS Number:
Molecular Weight:
73.09
EC Number:
200-679-5
UNSPSC Code:
12352111
PubChem Substance ID:
Beilstein/REAXYS Number:
605365
MDL number:
Quality Level
vapor pressure
2.7 mmHg ( 20 °C)
assay
≥99% (GC)
autoignition temp.
833 °F
expl. lim.
15.2 %
impurities
≤0.1% water (Karl Fischer)
bp
153 °C (lit.)
mp
−61 °C (lit.)
density
0.944 g/mL (lit.)
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General description
N,N-Dimethylformamide (DMF) is the commonly employed solvent for chemical reactions. DMF is a useful solvent employed for the isolation of chlorophyll from plant tissues.† It is widely employed reagent in organic synthesis. It plays multiple roles in various reactions such as solvent, dehydrating agent, reducing agent as well as catalyst. It is a multipurpose building block for the synthesis of compounds containing -O, -CO, -NMe2, -CONMe2, -Me, -CHO as functional groups.†
Application
Solvent for many hydrophobic organic compounds.
signalword
Danger
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Flam. Liq. 3 - Repr. 1B
Storage Class
3 - Flammable liquids
wgk
WGK 2
flash_point_f
135.5 °F - closed cup
flash_point_c
57.5 °C - closed cup
Regulatory Information
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An improved method for the determination of phytoplankton chlorophyll using N, N-dimethylformamide.
Suzuki R and Ishimaru T.
Journal of the Oceanographical Society of Japan, 46(4), 190-194 (1990)
Shape-dependent evolution of Au@ Ag core- shell nanocrystals by PVP-assisted N,N-dimethylformamide reduction.
Tsuji M, et al.
Crystal Growth & Design, 8(7), 2528-2536 (2008)
R Moran et al.
Plant physiology, 65(3), 478-479 (1980-03-01)
Photosynthetic pigments from etiolated cucumber (Cucumis sativus var. Beit Alpha improved, Hazera Co., Gedera) cotyledons were extracted by direct immersion of the intact cotyledons into the solvent N,N-dimethylformamide (DMF). The solvent is especially efficient when pigment concentration is low; time
S Ollier et al.
Journal of dairy science, 97(8), 4942-4954 (2014-06-03)
A cow's risk of acquiring a new intramammary infection during the dry period increases with milk production at drying off and decreases as mammary gland involution progresses. A method commonly used to reduce milk production is a drastic reduction in
Kun Liu et al.
Nanoscale, 4(20), 6574-6580 (2012-09-15)
Studies on the self-assembly of metal nanoparticles (NPs) in the presence of ions are motivated by the biosensing applications of NP clusters and the capability to control the morphology of clusters of oppositely charged NPs. The effect of ions has
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